1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. AMCase/CHIA 蛋白, Mouse (HEK293, His)

AMCase/CHIA 蛋白, Mouse (HEK293, His)

目录号: HY-P77559
产品使用指南

AMCase/CHIA 蛋白是一种酶,是几丁质酶家族的成员,可水解几丁质(真菌细胞壁的组成部分)。它在针对真菌感染的免疫反应中起着至关重要的作用。AMCase/CHIA 蛋白作为治疗靶点的潜力在于其调节免疫系统的能力及其参与过敏性疾病和哮喘的能力。AMCase/CHIA 蛋白, Mouse (HEK293, His) 是重组的 AMCas/CHIA 蛋白,由 HEK293 表达,带有 C-His 标签。AMCase/CHIA 蛋白, Mouse (HEK293, His) 全长 452 个氨基酸,分子量为 53-60 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

AMCase/CHIA Protein, an enzyme, is a member of the chitinase family that hydrolyzes chitin, a component of the fungal cell wall. It plays a crucial role in the immune response against fungal infections. AMCase/CHIA Protein's potential as a therapeutic target lies in its ability to modulate the immune system and its involvement in allergic diseases and asthma. AMCase/CHIA Protein, Mouse (HEK293, His) is the recombinant mouse-derived AMCase/CHIA protein, expressed by HEK293 , with C-His labeled tag. The total length of AMCase/CHIA Protein, Mouse (HEK293, His) is 452 a.a., with molecular weight of 53-60 kDa.

研究背景

AMCase/CHIA 蛋白是参与几丁质和几丁三糖降解的重要酶,几丁质和几丁三糖是真菌、线虫和其他病原体细胞壁的重要组成部分。这种蛋白质被认为在防御这些病原体方面发挥着重要作用,有助于人体的免疫反应,特别是 2 型辅助 T 细胞 (Th2) 免疫反应。它还参与对白细胞介素 13 (IL-13) 的反应以及随后由 IL-13 引起的炎症。此外,AMCase/CHIA 蛋白刺激肺上皮细胞产生趋化因子,保护肺上皮细胞免于凋亡,促进 AKT1 磷酸化。它在炎症反应中发挥作用并保护细胞免于凋亡的能力受到异糖脒的阻碍,表明碳水化合物结合对其功能至关重要。唾液和胃液中 AMCase/CHIA 蛋白的存在进一步表明其作为消化酶的作用。

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

Q91XA9 (Y22-P473)

基因 ID
蛋白结构
N-term
CHIA (Y22-P473)
Accession # Q91XA9
His
C-term
同用名
Acidic mammalian chitinase; AMCase; CHIA; CHIT2; EC 3.2.1.14; Chia1; YNL
分子量

53-60 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

AMCase/CHIA Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
AMCase/CHIA Protein, Mouse (HEK293, His)
目录号:
HY-P77559
需求量: