Animal-Free FGF-22 蛋白, Human (His)

FGF-22 Protein, multifaceted in physiological processes, influences fasting response, glucose homeostasis, lipolysis, and lipogenesis.It stimulates in vitro cell proliferation and may contribute to hair development.Functionally, FGF-22 forms complexes with FGFR1 and FGFR2, integral to FGF signaling pathways.Interactions with FGFBP1 highlight its role in finely tuned regulatory networks governing cellular and metabolic activities.Animal-Free FGF-22 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-22 protein, expressed by E.coli , with N-SUMO, N-His labeled tag.

FGF-22 是一种多方面的蛋白质，复杂地参与多种生理过程，包括禁食反应、葡萄糖稳态、脂肪分解和脂肪生成。除了其代谢作用之外，FGF-22 还具有刺激体外细胞增殖的能力，突出了其对细胞动力学的影响。此外，该蛋白质可能有助于头发发育的复杂过程。从功能上讲，FGF-22 参与重要的分子相互作用，与 FGFR1 和 FGFR2（FGF 信号通路的重要参与者）形成复合物。此外，它与 FGFBP1 相互作用，进一步强调其参与调控各种细胞和代谢活动的精细调节网络。

The ED₅₀ is <2 ng/mL as measure by its ability to induce 3T3 cells proliferation.

Human

E. coli

N-SUMO

Q9HCT0 (T23-S170)

27006  [NCBI]

TPSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS

Approximately 29.35 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 8.0, trehalose.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 10 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.