Animal-Free IL-32 alpha 蛋白, Human (His)

IL-32 alpha Protein, a cytokine, potentially contributes to innate and adaptive immune responses. It induces TNFA/TNF-alpha and IL8, activating typical cytokine signal pathways, including NF-kappa-B and p38 MAPK. Animal-Free IL-32 alpha Protein, Human (His) is the recombinant human-derived animal-FreeIL-32 alpha protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-32 alpha Protein, Human (His) is 131 a.a., with molecular weight of ~15.72 kDa.

IL-32 α 蛋白被归类为细胞因子，与先天性和适应性免疫反应有关。该蛋白能够诱导多种细胞因子的表达，包括 TNFA/TNF-α 和 IL8，从而影响炎症环境。此外，IL-32 α 触发的信号通路涵盖了 NF-kappa-B 和 p38 MAPK 的典型通路，突显了其参与协调与免疫调节相关的多种细胞反应。这强调了 IL-32 α 在复杂的免疫信号级联网络中的潜在重要性，有助于调节炎症和免疫过程。

Measure by its ability to induce TNF alpha secretion in RAW264.7 cells. The ED₅₀ for this effect is <10 μg/mL.

Human

E. coli

C-His

P24001-4 (M1-K131)

9235  [NCBI]

MCFPKVLSDDMKKLKARMHQAIERFYDKMQNAESGRGQVMSSLAELEDDFKEGYLETVAAYYEEQHPELTPLLEKERDGLRCRGNRSPVPDVEDPATEEPGESFCDKSYGAPRGDKEELTPQKCSEPQSSK

Approximately 15.72 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 8.0, trehalose.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.