Animal-Free LIX/CXCL5 蛋白, Mouse (His)

The LIX/CXCL5 protein may recruit inflammatory cells to injured or infected tissues, suggesting a role in the immune response.Both GCP-2(1-78) and the more potent GCP-2(9-78) variant attract and activate neutrophils.Animal-Free LIX/CXCL5 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeLIX/CXCL5 protein, expressed by E.coli , with N-His labeled tag.

Animal-Free LIX/CXCL5 蛋白可能参与炎症细胞向受伤或感染组织的募集，表明其在免疫反应中的作用。该蛋白的 GCP-2(1-78) 和更有效的 GCP-2(9-78) 变体都在吸引中性粒细胞方面发挥作用，并参与这些免疫细胞的激活。在结构上，该蛋白质以单体存在，也可以形成同二聚体，强调了其多功能性和分子相互作用的潜力。Animal-Free LIX/CXCL5 吸引和激活中性粒细胞的能力凸显了其在协调免疫反应和与炎症相关的细胞过程中的重要性。

Measure by its ability to chemoattract BaF3 cells transfected with human CXCR2. The ED₅₀ for this effect is <100 ng/mL

Mouse

E. coli

N-His

P50228 (V45-A118)

20311  [NCBI]

VIAATELRCVCLTVTPKINPKLIANLEVIPAGPQCPTVEVIAKLKNQKEVCLDPEAPVIKKIIQKILGSDKKKA

Approximately 8.92 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 7.4, trehalose.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.