AQP1 蛋白, Human (GST)

The AQP1 protein forms water-specific channels that allow water to cross red blood cells and renal proximal tubule membranes. AQP1 Protein, Human (GST) is the recombinant human-derived AQP1 protein, expressed by E. coli , with N-GST labeled tag. The total length of AQP1 Protein, Human (GST) is 50 a.a., with molecular weight of ~31 kDa.

AQP1 是一种水特异性通道，在增强红细胞和肾近曲小管质膜的通透性方面发挥着关键作用，允许水沿着渗透梯度移动。它形成同源四聚体，是锚蛋白-1 复合物的关键成分，锚蛋白-1 复合物是一种对维持红细胞膜稳定性和形状至关重要的多蛋白组装体。在红细胞中，ankyrin-1 复合物由 AQP1 以及 ANK1、RHCE、RHAG、SLC4A1、EPB42、GYPA 和 GYPB 组成。AQP1 与 EPHB2 的相互作用进一步凸显了 AQP1 的多功能性，有助于内耳内淋巴的产生。此外，AQP1 参与涉及 STOM 的复合体。该蛋白质通过其 N 端区域与 ANK1 以及通过其 C 端区域与 EPB42 建立相互作用，强调其参与各种细胞过程和蛋白质组装。

Human

E. coli

N-GST

P29972 (G220-K269)

358  [NCBI]

GALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK

Approximately 31 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm solution of Tris-based buffer, 50% Glycerol or 50 mM Tris-HCL, 300 mM NaCL, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.