ATP1B2 蛋白, Human (HEK293, His)

The ATP1B2 protein is the non-catalytic component of ATP hydrolase and promotes Na(+)/K(+) ion exchange across the plasma membrane. Its role is critical in mediating cell adhesion of neurons and astrocytes, promoting sticky cell interactions. ATP1B2 Protein, Human (HEK293, His) is the recombinant human-derived ATP1B2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ATP1B2 Protein, Human (HEK293, His) is 223 a.a., with molecular weight of 40-60 kDa.

ATP1B2 蛋白作为活性酶的非催化成分，负责催化 ATP 水解以及跨质膜的 Na(+) 和 K(+) 离子交换。虽然 beta-2 亚基的精确功能仍然难以捉摸，但它在介导神经元和星形胶质细胞的细胞粘附方面发挥着至关重要的作用，有助于这些细胞之间的粘附相互作用。此外，ATP1B2 促进神经突生长，表明它参与调节神经元投射延伸的复杂过程。这些细胞功能凸显了 ATP1B2 不仅在离子运输方面的重要性，而且在介导粘附和促进神经网络结构发育方面的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

N-6*His

P14415 (D68-T290)

482  [NCBI]

DHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT

Approximately 40-60 kDa due to the glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.