B2M/Beta-2 microglobulin 蛋白, Mouse (HEK293, His)

Beta-2 microglobulin (B2M) is vital in presenting antigens to the immune system through MHC class I molecules. It forms a heterodimer with an alpha chain to create MHC class I molecules. B2M also forms a heterotrimer with MR1 and a metabolite antigen, enhancing antigen presentation and immune recognition. B2M's molecular interactions facilitate immune system functioning and foreign substance recognition. B2M/Beta-2 microglobulin Protein, Mouse (HEK293, His) is the recombinant mouse-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Mouse (HEK293, His) is 99 a.a., with molecular weight of ~14.5 kDa.

Beta-2 微球蛋白 (B2M) 蛋白是 I 类主要组织相容性复合体 (MHC) 的重要组成部分，在向免疫系统呈递肽抗原方面发挥着关键作用。它与 α 链形成异二聚体，共同构成主要组织相容性复合物 I 类分子。此外，B2M 可以与 MR1 和代谢物抗原形成异源三聚体，进一步促进抗原呈递和免疫识别过程。通过参与这些分子相互作用，B2M 有助于免疫系统的正常运作和外来物质的识别。

Mouse

HEK293

C-His

P01887 (I21-M119)

12010  [NCBI]

IQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIEIQMLKNGKKIPKVEMSDMSFSKDWSFYILAHTEFTPTETDTYACRVKHDSMAEPKTVYWDRDM

Approximately 14.5 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.