2. 重组蛋白
  3. Immune Checkpoint Proteins CD Antigens
  4. Inhibitory Checkpoint Molecules Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins
  5. B7-2/CD86
  6. B7-2/CD86 蛋白, Mouse (HEK293, Fc)

B7-2/CD86 蛋白, Mouse (HEK293, Fc)

目录号: HY-P7635
产品使用指南

B7-2/CD86 蛋白, Mouse (HEK293, Fc)是 CLTA4 的配体，在小鼠 B细胞上表达，可作为 T 细胞活化的共刺激分子。

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SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

B7-2/CD86 Protein, Mouse (HEK293, Fc), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation[1][2].
研究背景

抑制CD28与B7-2分子的相互作用可能代表治疗肺粘膜过敏性炎症的新治疗靶点。过敏原刺激后，肺 B 细胞上的 B7-2（而非 B7-1）上调[1][2]。
种属

Mouse
表达系统

HEK293
标签

C-Fc
蛋白编号

P42082 (V26-E245)
基因 ID
蛋白结构
N-term
B7-2 (V26-E245)
Accession # P42082
Fc
C-term
中文名
重组小鼠B7-2, C-Fc 标签 (HEK293-表达)
同用名
rMuB7-2, C-Fc; T-lymphocyte activation antigen CD86; Early T-cell costimulatory molecule 1; ETC-1; CD86
氨基酸序列

VETQAYFNGTAYLPCPFTKAQNISLSELVVFWQDQQKLVLYEHYLGTEKLDSVNAKYLGRTSFDRNNWTLRLHNVQIKDMGSYDCFIQKKPPTGSIILQQTLTELSVIANFSEPEIKLAQNVTGNSGINLTCTSKQGHPKPKKMYFLITNSTNEYGDNMQISQDNVTELFSISNSLSLSFPDGVWHMTVVCVLETESMKISSKPLNFTQEFPSPQTYWKE-Fctag

分子量

65-110 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)
参考文献

B7-2/CD86 Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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