2. Gene
  3. Cd86 - CD86 antigen Gene

Cd86 - CD86 antigen Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2

基因 ID: 12524 | 基因类型: protein coding

关于 Cd86

功能概要

Predicted to enable signaling receptor binding activity. Involved in several processes, including CD40 signaling pathway; activation of Phospholipase C activity; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; defense response to virus; and positive regulation of T cell proliferation. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Is expressed in central nervous system and retina. Used to study Guillain-Barre syndrome. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd86 基因产物(1)

mRNA Protein Name
NM_019388.3 NP_062261.3 T-lymphocyte activation antigen CD86 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23241883 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell activation IDA
IDA: 通过直接分析推断
19734906 MGI
involved in B cell activation IDA
IDA: 通过直接分析推断
23241883 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
19047410 MGI
acts upstream of or within defense response to virus IDA
IDA: 通过直接分析推断
17277142 MGI
acts upstream of or within positive regulation of T cell proliferation IGI
IGI: 通过遗传相互作用推断
23793062 MGI
involved in positive regulation of immunoglobulin production IDA
IDA: 通过直接分析推断
23241883 MGI
involved in positive regulation of non-canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
23241883 MGI
involved in toll-like receptor 3 signaling pathway IMP
IMP: 通过突变表型推断
25158758 MGI
acts upstream of or within toll-like receptor signaling pathway IDA
IDA: 通过直接分析推断
19734906 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
12801066 MGI
located in intracellular membrane-bounded organelle IDA
IDA: 通过直接分析推断
16708399 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

T-lymphocyte activation antigen CD86

activation B7-2 antigen

early T cell costimulatory molecule-1

重组 Cd86 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7635 B7-2/CD86 Protein, Mouse (HEK293, Fc) P42082 (V26-E245) ≥95%
HY-P7638 B7-2/CD86 Protein, Mouse (HEK293, His) P42082 (V24-K244) ≥95%

Cd86 抗体

目录号 产品名 应用 反应物种
HY-P83710m Rat Anti-Mouse CD86 Antibody (FITC) FC Mouse

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-W016773 1,10-Decanediol 99.93% Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99821 Ravagalimab Inhibitor 99.31% Phase 2
Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148980A Polyinosinic acid sodium / 否
HY-150749A ODN D-SL03 sodium 99.82% 否
HY-150749 ODN D-SL03 Inducer 99.82% 否
HY-148980 Polyinosinic acid / 否
HY-143410 Anti-inflammatory agent 16 Inhibitor / 否
HY-144675 LSD1-IN-13 Inhibitor / 否
HY-144675A LSD1-IN-13 hydrochloride Inhibitor / 否
HY-150740 ODN 21595 Inhibitor / 否
HY-150740A ODN 21595 sodium Inhibitor / 否
HY-152201 BTK-IN-18 Inhibitor / 否
HY-160227 ORN 06 Activator / 否
HY-161833 HSP90-IN-31 Inhibitor / 否
HY-170403 LSD1-IN-38 Inhibitor / 否
HY-RS02274 CD86 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-168384 M04 / 否
HY-169819 Calcium influx inducer compound 634 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd86 NCBI NCBI:942
Macaca fascicularis Cd86 NCBI NCBI:102147235
Leporidae Cd86 NCBI
Rattus norvegicus Cd86 NCBI NCBI:56822
Macaca mulatta Cd86 NCBI NCBI:714390
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