2. Gene
  3. Cd86 - CD86 molecule Gene

Cd86 - CD86 molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: B7-2

基因 ID: 56822 | 基因类型: protein coding

关于 Cd86

功能概要

Enables signaling receptor binding activity. Involved in several processes, including defense response to Other organism; negative regulation of T cell anergy; and positive regulation of activated T cell proliferation. Located in cell surface. Used to study adult T-cell leukemia and bronchiolitis obliterans. Biomarker of asthma; corneal disease; middle cerebral artery infarction; and orchitis. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd86 基因产物(1)

mRNA Protein Name
NM_020081.2 NP_064466.1 T-lymphocyte activation antigen CD86 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
17289805 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell proliferation involved in immune response IEP
IEP: 通过表达模式推断
20500684 RGD
involved in cellular response to cytokine stimulus IEP
IEP: 通过表达模式推断
19642897 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
21039614 RGD
involved in cellular response to metal ion IEP
IEP: 通过表达模式推断
19653805 RGD
involved in defense response to virus IEP
IEP: 通过表达模式推断
20603637 RGD
involved in myeloid dendritic cell differentiation IEP
IEP: 通过表达模式推断
21039614 RGD
involved in negative regulation of T cell anergy IMP
IMP: 通过突变表型推断
18424705 RGD
involved in positive regulation of T cell proliferation IMP
IMP: 通过突变表型推断
19107191 RGD
involved in positive regulation of activated T cell proliferation IDA
IDA: 通过直接分析推断
9237108 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
17935670 RGD
involved in response to type II interferon IEP
IEP: 通过表达模式推断
16839612 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
18704298 RGD
involved in response to yeast IEP
IEP: 通过表达模式推断
19494083 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
9237108 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

T-lymphocyte activation antigen CD86

cd86 antigen

membrane glycoprotein

重组 Cd86 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7636 B7-2/CD86 Protein, Rat (HEK293, His) O35531 (V29-K247) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-W016773 1,10-Decanediol 99.93% Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99821 Ravagalimab Inhibitor 99.31% Phase 2
Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148980A Polyinosinic acid sodium / 否
HY-150749A ODN D-SL03 sodium 99.82% 否
HY-150749 ODN D-SL03 Inducer 99.82% 否
HY-148980 Polyinosinic acid / 否
HY-143410 Anti-inflammatory agent 16 Inhibitor / 否
HY-144675 LSD1-IN-13 Inhibitor / 否
HY-144675A LSD1-IN-13 hydrochloride Inhibitor / 否
HY-150740 ODN 21595 Inhibitor / 否
HY-150740A ODN 21595 sodium Inhibitor / 否
HY-152201 BTK-IN-18 Inhibitor / 否
HY-160227 ORN 06 Activator / 否
HY-161833 HSP90-IN-31 Inhibitor / 否
HY-RS02274 CD86 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd86 NCBI NCBI:942
Macaca fascicularis Cd86 NCBI NCBI:102147235
Mus musculus Cd86 NCBI NCBI:12524
Leporidae Cd86 NCBI
Macaca mulatta Cd86 NCBI NCBI:714390
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