1. 重组蛋白
  2. Enzymes & Regulators
  3. BACH2 蛋白, Human (Sf9, His, Strep)

BACH2 蛋白, Human (Sf9, His, Strep)

目录号: HY-P701534
产品使用指南

BACH2 是一种多功能转录调节因子,既充当阻遏子又充当激活子,并识别 Maf 识别元件 (MARE) 来协调 MAFK 的转录调控。在氧化应激期间,BACH2 通过抑制 HMOX1 诱导细胞凋亡。BACH2 蛋白, Human (Sf9, His, Strep) 是重组的 BACH2 蛋白,由 Sf9 insect cells 表达,带有 N-Strep, N-8*His 标签。BACH2 蛋白, Human (Sf9, His, Strep) 全长 840 个氨基酸。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

BACH2 is a multifunctional transcriptional regulator that acts as both a repressor and an activator and recognizes Maf recognition elements (MAREs) to coordinate the transcriptional regulation of MAFKs. During oxidative stress, BACH2 induces apoptosis by inhibiting HMOX1. BACH2 Protein, Human (Sf9, His, Strep) is the recombinant human-derived BACH2 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of BACH2 Protein, Human (Sf9, His, Strep) is 840 a.a., .

研究背景

BACH2 是一种多功能转录调节因子,具有抑制子和激活子的双重作用。它识别 Maf 识别元件 (MARE),与 MAFK 一起协调转录激活和抑制。为了应对氧化应激,BACH2 通过抑制抗凋亡因子 HMOX1 来诱导细胞凋亡。此外,它在适应性免疫中发挥着关键作用,对维持调节性 T 细胞功能和 B 细胞成熟至关重要。BACH2 与 Maf 相关转录因子形成同二聚体、二硫键连接和异二聚体,强调其参与复杂的调控网络。此外,BACH2 作为肌动蛋白核输入的正调节因子,强调了其在细胞过程中的多种功能。

种属

Human

表达系统

Sf9 insect cells

标签

N-Strep;N-8*His

蛋白编号

Q9BYV9 (S2-T841)

基因 ID

60468

蛋白结构
N-term
8*His-Strep
BACH2 (S2-T841)
Accession # Q9BYV9
C-term
同用名
BACH2; Transcription regulator protein BACH2; BTB and CNC homolog 2
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

BACH2 Protein, Human (Sf9, His, Strep) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
BACH2 Protein, Human (Sf9, His, Strep)
目录号:
HY-P701534
需求量: