BTN2A2 蛋白, Mouse (HEK293, His)

BTN2A2 protein inhibits CD4 and CD8 T-cell proliferation activated by anti-CD3 antibodies. It regulates T-cell metabolism, suppressing IL2 and IFNG cytokine secretion. BTN2A2 plays a pivotal role in immune response modulation, maintaining immune homeostasis by limiting T-cell activation and effector functions. BTN2A2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived BTN2A2 protein, expressed by HEK293 , with C-His labeled tag. The total length of BTN2A2 Protein, Mouse (HEK293, His) is 215 a.a., with molecular weight of 40-50 kDa.

BTN2A2 蛋白起到抑制剂的作用，阻止被抗 CD3 抗体激活的 CD4 和 CD8 T 细胞的增殖。此外，它还对 T 细胞代谢进行调节控制，并抑制细胞因子 IL2 和 IFNG 的分泌。这种抑制反映了 BTN2A2 通过限制 T 细胞的激活和效应功能来调节免疫反应和维持免疫稳态的关键作用。

Mouse

HEK293

C-His

A4QPC6-1 (Q30-S244)

/

40-50 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS(pH 7.4). Normally 8% Trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.