C-Reactive 蛋白, Human (His)

C-Reactive Protein, an acute-phase protein, is a marker of inflammation and is produced by the liver. It is used as a diagnostic tool to assess the presence and severity of inflammation in various diseases. C-Reactive Protein's role in inflammation detection and its clinical significance in disease management make it a subject of interest in medical research. C-Reactive Protein, Human (His) is the recombinant human-derived C-Reactive protein, expressed by E. coli , with C-6*His labeled tag. The total length of C-Reactive Protein, Human (His) is 206 a.a., with molecular weight of ~27.0 kDa.

C反应蛋白（CRP）表现出与宿主防御相关的各种功能。它以钙依赖性方式与磷酸胆碱结合，促进凝集、细菌荚膜肿胀、吞噬作用和补体固定。CRP 还能够与 DNA 和组蛋白相互作用，并且可以清除受损循环细胞释放的核物质。

Immobilized Human CRP-His at 10 μg/mL (100 μl/well) can bind Human CD32a-His* : Biotinylated by NHS-biotin prior to testing.The ED₅₀ is 7.64 μg/mL.

Human

E. coli

C-6*His

P02741 (Q19-P224)

1401  [NCBI]

QTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP

Approximately 27.0 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 2 M Urea, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.