Cadherin-3 蛋白, Cynomolgus (547a.a, HEK293, His)

Cadherin-9 Protein, a calcium-dependent cell adhesion molecule, functions within cellular interactions. Exhibiting calcium-dependent adhesion, CDH9 prefers homophilic interactions, connecting cells. This unique feature suggests a potential role in sorting heterogeneous cell types. The calcium-dependent mechanism underscores cadherins' regulatory role in cellular cohesion within intercellular junctions, maintaining tissue integrity and function. Cadherin-3 Protein, Cynomolgus (547a.a, HEK293, His) is the recombinant cynomolgus-derived Cadherin-3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-3 Protein, Cynomolgus (547a.a, HEK293, His) is 547 a.a., with molecular weight of 70-80 kDa.

Cadherin-9 是一种钙依赖性细胞粘附蛋白，是复杂的细胞相互作用网络的一部分。像 CDH9 这样的钙粘蛋白表现出钙依赖性粘附，表现出对同质相互作用的偏好，在连接细胞时与自身相互作用。这一独特的特征使钙粘蛋白有可能在异质细胞类型的分选中发挥作用。钙依赖性机制强调了钙粘蛋白在细胞间连接内的细胞凝聚和组织中的调节作用，有助于组织完整性和功能的整体维持。

Anti-CDH3 Antibody captured on CM5 Chip via Protein A can bind Cynomolgus CDH3, His Tag with an affinity constant of 0.37 μM as determined in SPR assay (Biacore T200).

Cynomolgus

HEK293

C-His

XP_005592414.1 (D108-G654)

102142204  [NCBI]

70-80 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from 0.22μm filtered solution in 20mM PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.