CADM4/IGSF4C 蛋白, Mouse (HEK293, His)

CADM4/IGSF4C Protein, vital for cell-cell adhesion, has calcium- and magnesium-independent activity. Its adhesive role suggests a function in tissue integrity. Additionally, it may act as a tumor suppressor, inhibiting cellular proliferation and tumorigenesis. As a monomer and homodimer, CADM4/IGSF4C Protein dynamically interacts, coordinating adhesion and potential tumor suppression. CADM4/IGSF4C Protein, Mouse (HEK293, His) is the recombinant mouse-derived CADM4/IGSF4C protein, expressed by HEK293 , with C-His labeled tag.

CADM4/IGSF4C 蛋白在细胞间粘附中发挥着至关重要的作用，表现出不依赖于钙和镁的活性。它参与介导细胞之间的粘附相互作用，表明其在维持组织完整性方面具有潜在作用。除了其粘附功能外，CADM4/IGSF4C 蛋白可能还具有肿瘤抑制活性，这表明其在调节细胞增殖和抑制肿瘤发生方面具有潜在意义。作为单体和同二聚体，CADM4/IGSF4C 蛋白可能参与动态细胞相互作用，有助于协调与粘附和潜在肿瘤抑制相关的各种生理过程。

Measured by its ability to inhibit the proliferation of A549 cells. The ED₅₀ for this effect is 0.9491 μg/mL, corresponding to a specific activity is 1.054×10³ units/mg.

Mouse

HEK293

C-6*His

Q8R464 (P21-A324)

260299  [NCBI]

PGTGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLVPRSRPAAVLRWYRDRKELKGVSSGQENGKVWSVASTVRFRVDRKDDGGIVICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEAANKHGHARALYVLVVYDPGAVVEAQTSVPYA

Approximately 48-70 kDa due to the glycosylation.

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.