1. 重组蛋白
  2. CD Antigens Enzymes & Regulators
  3. Endothelial cell CD Proteins Hydrolases (EC 3)
  4. BST1/CD157
  5. CD157 蛋白, Human (HEK293, Fc)

CD157 蛋白, Human (HEK293, Fc)

目录号: HY-P7792
产品使用指南

CD157 蛋白, Human (HEK293, Fc)是一种在 HEK 293 细胞中表达的,C 末端有 Fc 标签的重组人 CD157。CD157 蛋白 是细胞表面受体和免疫调节分子。

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描述

CD157 Protein, Human (HEK293, Fc) is a recombinant human CD157 expressed in HEK 293 cells with a C-Fc tag at the C-terminus. CD157 Protein is a cell surface receptor and an immunoregulatory molecule[1][2].

研究背景

CD157,也称为骨髓基质细胞抗原 1 (BST-1),是一种多效性胞外酶,属于 CD38 家族,属于数量不断增加的白细胞表面分子,已知可独立充当受体和酶。BST-1 是一种糖基磷脂酰肌醇锚定蛋白,可刺激前 B 细胞生长,并具有二磷酸腺苷 (ADP)-核糖基环化酶和环 ADP-核糖 (cADPR) 水解酶活性[1][2]

种属

Human

表达系统

HEK293

标签

C-Fc

蛋白编号

Q10588 (G29-K292)

基因 ID

683  [NCBI]

蛋白结构
N-term
CD157 (G29-K292)
Accession # Q10588
Fc
C-term
中文名
重组人 CD157, C-Fc (HEK 293 表达)
同用名
ADP-ribosyl cyclase; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST1; Cyclic ADP-ribose hydrolase 2; CD157
氨基酸序列

GARARWRGEGTSAHLRDIFLGRCAEYRALLSPEQRNKNCTAIWEAFKVALDKDPCSVLPSDYDLFINLSRHSIPRDKSLFWENSHLLVNSFADNTRRFMPLSDVLYGRVADFLSWCRQKNDSGLDYQSCPTSEDCENNPVDSFWKRASIQYSKDSSGVIHVMLNGSEPTGAYPIKGFFADYEIPNLQKEKITRIEIWVMHEIGGPNVESCGEGSMKVLEKRLKDMGFQYSCINDYRPVKLLQCVDHSTHPDCALKSAAAATQRK-Fctag

分子量

Approximately 75 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
参考文献
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD157 Protein, Human (HEK293, Fc)
目录号:
HY-P7792
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