CD2 蛋白, Mouse (HEK293, His)

CD2 protein binds to identical proteins and is crucial for immune processes. It participates in T cell activation, cell-cell adhesion, and cytokine production. CD2 is located in cell junctions and the external side of the plasma membrane. It is highly expressed in immune-related tissues like the thymus and spleen, suggesting its importance in immune function. CD2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CD2 Protein, Mouse (HEK293, His) is 181 a.a., with molecular weight of approximately 33.79 kDa.

CD2 是一种细胞表面糖蛋白，参与相同的蛋白质结合活性，并在各种免疫过程中发挥着至关重要的作用。CD2 预计参与 T 细胞激活、异型细胞间粘附和细胞因子产生的正向调节，主要位于细胞成分中，例如细胞间连接和质膜外侧。CD2作为质膜的锚定成分，在胸腺和脾脏等免疫系统相关组织中呈现偏向表达，表达水平显着，分别为RPKM 30.1和RPKM 18.0，表明其在免疫功能和调节中的重要性。

Measured by the ability of the immobilized protein to support the adhesion of Jurkat human T-lymphocyte leukemia cells. The ED₅₀ for this effect is 383.6 ng/ml, corresponding to a specific activity is 2.607×10^3 units/mg.

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  Measured by the ability of the immobilized protein to support the adhesion of Jurkat human T-lymphocyte leukemia cells. The ED₅₀ for this effect is 383.6 ng/mL, corresponding to a specific activity is 2.607×10³ units/mg.

Mouse

HEK293

C-10*His

NP_038514.1 (R23-S203)

12481  [NCBI]

RDNETIWGVLGHGITLNIPNFQMTDDIDEVRWVRRGTLVAEFKRKKPPFLISETYEVLANGSLKIKKPMMRNDSGTYNVMVYGTNGMTRLEKDLDVRILERVSKPVIHWECPNTTLTCAVLQGTDFELKLYQGETLLNSLPQKNMSYQWTNLSAPFKCEAINPVSKESKTEVVNCPEKGLS

approximately 33.79 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 (Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.) or 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.