1. 重组蛋白
  2. Immune Checkpoint Proteins CD Antigens
  3. Stimulatory Immune Checkpoint Molecules Macrophage CD Proteins Monocyte CD Proteins Stem Cell CD Proteins Dendritic Cell CD Proteins
  4. CD200
  5. CD200 蛋白, Cynomolgus (HEK293, His)

CD200 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700670
产品使用指南

CD200 蛋白作为 T 细胞增殖的共刺激物发挥作用,并参与多种组织中骨髓细胞活性的潜在调节。通过其 N 端 Ig 样结构域,CD200CD200R1 相互作用,建立可能有助于调节免疫反应和细胞活动的分子相互作用。CD200 蛋白, Cynomolgus (HEK293, His) 是重组的 CD200 蛋白,由 HEK293 表达,带有 C-His 标签。CD200 蛋白, Cynomolgus (HEK293, His) 全长 202 个氨基酸,分子量为 45-55 kDa。

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描述

CD200 protein functions as a costimulator of T-cell proliferation and is implicated in the potential regulation of myeloid cell activity across various tissues. Through their N-terminal Ig-like domains, CD200 interacts with CD200R1, establishing a molecular interaction that likely contributes to the modulation of immune responses and cellular activities. CD200 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD200 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD200 Protein, Cynomolgus (HEK293, His) is 202 a.a., with molecular weight of 45-55 kDa.

研究背景

CD200 蛋白在免疫调节中发挥着关键作用,作为促进 T 细胞增殖的共刺激分子。此外,正如基于相似性的推论所表明的,CD200 参与了跨不同组织的骨髓细胞活性的潜在调节。CD200 与其受体 CD200R1 之间的相互作用是通过它们各自的 N 端 Ig 样结构域促进的。这种相互作用可能有助于参与免疫反应和骨髓细胞功能的调节过程。CD200CD200R1 的结合强调了其在介导免疫细胞通讯和稳态方面的重要性,强调了其作为免疫调节关键参与者的潜力。

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

A0A2K5TQS2 (Q56-G257)

基因 ID

/

蛋白结构
N-term
CD200 (Q56-G257)
Accession # A0A2K5TQS2
His
C-term
同用名
CD200; MOX1; MOX2; My033; MRC; OX-2; OX2
分子量

45-55 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD200 Protein, Cynomolgus (HEK293, His)
目录号:
HY-P700670
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