1. 重组蛋白
  2. Immune Checkpoint Proteins Receptor Proteins
  3. Stimulatory Immune Checkpoint Molecules
  4. CD200R
  5. CD200R4
  6. CD200R4 蛋白, Mouse (HEK293, His)

CD200R4 蛋白, Mouse (HEK293, His)

目录号: HY-P77318
COA 产品使用指南

CD200R4 蛋白对 TYROBP 受体募集或表面表达有显着贡献,表明其在免疫调节或信号传导过程中的作用。与 TYROBP 的分子相互作用强调了 CD200R4 的功能,其可能影响下游细胞反应并介导 TYROBP 相关信号传导事件。CD200R4 蛋白, Mouse (HEK293, His) 是重组的 CD200R4 蛋白,由 HEK293 表达,带有 C-His 标签。CD200R4 蛋白, Mouse (HEK293, His) 全长 216 个氨基酸,分子量约为 ~40-75 kDa。

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规格 价格 是否有货 数量
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5 μg ¥630 In-stock
10 μg ¥1070 In-stock
50 μg ¥3000 In-stock
100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The CD200R4 protein significantly contributes to TYROBP receptor recruitment or surface expression, suggesting its role in immune regulation or signaling processes. Molecular interactions with TYROBP underscore the function of CD200R4, which may influence downstream cellular responses and mediate TYROBP-related signaling events. CD200R4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD200R4 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD200R4 Protein, Mouse (HEK293, His) is 216 a.a., with molecular weight of ~40-75 kDa.

研究背景

CD200R4 蛋白在 TYROBP 受体的募集或表面表达中发挥重要作用,表明其参与与免疫调节或信号传导相关的细胞过程。与 TYROBP 的相互作用强调了有助于 CD200R4 功能的分子关联,可能影响下游细胞反应。这种相互作用表明 CD200R4 在介导与 TYROBP 相关的信号事件中发挥作用,突出了其在免疫调节或涉及 TYROBP 信号通路的其他细胞活动中的重要性。

生物活性

Measured by its binding ability in a functional ELISA. When Recombinant Mouse CD200 R4 is present at 0.5 μg/mL can bind Recombinant Mouse CD200. The ED50 for this effect is 1.23 μg/mL.

  • Measured by its binding ability in a functional ELISA. When Recombinant Mouse CD200 R4 is present at 0.5 μg/mL can bind Recombinant Mouse CD200. The ED50 for this effect is 1.23 μg/mL.
种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

Q6XJV4 (T26-T241)

基因 ID

239849  [NCBI]

蛋白结构
N-term
CD200R4 (T26-T241)
Accession # Q6XJV4
His
C-term
同用名
Cell surface glycoprotein CD200 receptor 4; CD200RLa; Cd200r4
氨基酸序列

TDENQTIQNDSSSSLTQVNTTMSVQMDKKALLCCFSSPLINAVLITWIIKHRHLPSCTIAYNLDKKTNETSCLGRNITWASTPDHSPELQISAVALQHEGTYTCEIVTPEGNLEKVYDLQVLVPPEVTYFPGKNRTAVCEAMAGKPAAQISWTPDGDCVTKSESHSNGTVTVRSTCHWEQNNVSVVSCLVSHSTGNQSLSIELSQGTMTTPRSLLT

分子量

The protein migrates as an approximately 40-75 kDa band under reducing SDS-PAGE due to glycosylation.

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD200R4 Protein, Mouse (HEK293, His)
目录号:
HY-P77318
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