CD28 蛋白, Rat (HEK293, Fc)

CD28 Protein activates T-cells, promoting cell proliferation, cytokine production, and T-cell survival. It collaborates with TCR/CD3 ligation and CD40L costimulation to boost IL4 and IL10 production in T-cells. CD28 Protein forms a disulfide-linked homodimer and interacts with DUSP14. It also binds to CD80/B7-1 and CD86/B7-2/B70, and interacts with GRB2 (By similarity). CD28 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD28 protein, expressed by HEK293 , with C-hFc labeled tag.

CD28 蛋白通过诱导细胞增殖、细胞因子产生和促进 T 细胞存活，在 T 细胞激活中发挥至关重要的作用。它与 TCR/CD3 连接和 CD40L 共刺激结合使用，以增强 T 细胞中 IL4 和 IL10 的产生。CD28 蛋白通过二硫键形成同二聚体并与 DUSP14 相互作用。此外，它还与 CD80/B7-1 和 CD86/B7-2/B70 结合，并与 GRB2 相互作用（通过相似性）。

Rat

HEK293

C-hFc

P31042/EDL98926.1 (N20-K149)

25660  [NCBI]

Approximately 42 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.