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  2. Cd28 - Cd28 molecule Gene

Cd28 - Cd28 molecule Gene

中文名称:Cd28 分子

种属: Rattus norvegicus

同用名: CD28RNA

基因 ID: 25660 | 基因类型: protein coding

关于 Cd28

Primary_assembly 9: 62,166,192-62,194,685 forward strand.mRatBN7.2:CM026982.1

This gene has 3 transcripts (splice variants), 132 orthologues, 1 paralogue and is associated with 34 phenotypes. Biased expression in Thymus (RPKM 29.4), Spleen (RPKM 42.9) and 4 other tissues.

功能概要

实现相同的蛋白质结合活性。参与 T 细胞活化和 T 细胞共刺激。位于膜筏内。用于研究淋巴细胞减少症。该基因的人类直系同源物与多发性硬化症和 1 型糖尿病有关。与人 CD28(CD28 分子)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity. Involved in T cell activation and T cell costimulation. Located in membrane raft. Used to study lymphopenia. Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus. Orthologous to human CD28 (CD28 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd28 基因产物(1)

mRNA Protein Name
NM_013121.2 NP_037253.2 T-cell-specific surface glycoprotein CD28 precursor

Cd28 蛋白结构

Ig

Ig: cl11960 (21 - 137)

Ig

Ig: cd00096 (36 - 40)

Ig

Ig: cd00096 (52 - 56)

Ig

Ig: cd00096 (95 - 99)

Ig

Ig: cd00096 (109 - 114)

Ig

Ig: cd00096 (127 - 131)

  • 0
  • 100
  • 200
  • 218 a.a.
蛋白主名 其他名称

T-cell-specific surface glycoprotein CD28

CD28 antigen

重组 Cd28 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74309 CD28 Protein, Rat (HEK293, His) P31042 (N20-K149) ≥95%
HY-P74310 CD28 Protein, Rat (HEK293, Fc) P31042/EDL98926.1 (N20-K149) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd28 NCBI NCBI:940
Canis familiaris Cd28 NCBI NCBI:403646
Macaca fascicularis Cd28 NCBI NCBI:102146670
Mus musculus Cd28 NCBI NCBI:12487
Macaca mulatta Cd28 NCBI NCBI:705313