1. 天然产物
  2. 疾病研究领域
  3. 癌症
  4. Tiragolumab

Tiragolumab  (Synonyms: 替瑞利尤单抗; MTIG-7192A; RG-6058)

目录号: HY-P9986 纯度: 99.04%
COA

Tiragolumab 是一种与 T 细胞免疫球蛋白和 ITIM 结构域 (TIGIT) 结合的免疫检查点抑制剂。Tiragolumab 单独或与 PD-L1 抑制剂 Atezolizumab (HY-P9904) 联合使用,可能对多种实体恶性肿瘤有效,尤其是非小细胞肺癌 (NSCLC)。

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CAS No. : 1918185-84-8

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规格 价格 是否有货 数量
1 mg ¥1800
In-stock
5 mg ¥5400
In-stock
10 mg ¥8700
In-stock
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100 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tiragolumab is an immune checkpoint inhibitor binding to T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab, alone or in combination with the PD-L1 inhibitor Atezolizumab (HY-P9904), may be effective against multiple solid malignancies-most notably non-small cell lung cancer (NSCLC)[1][2].

IC50 & Target

TIGIT[1]

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

替瑞利尤单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG1 kappa
Biological Activity
  • Tiragolumab has a significant ADCP effect on CHO-K1/TIGIT cells in a dose-dependent manner.The EC50 for this effect is 189.43 ng/mL.
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tiragolumab
目录号:
HY-P9986
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