CD39 蛋白, Human (sf9, His)

The CD39 protein is an important regulator in the nervous system, coordinating purinergic neurotransmission by hydrolyzing ATP and other nucleotides. Its enzymatic ability can hydrolyze platelet-activated ADP into AMP, thereby effectively preventing platelet aggregation. CD39 Protein, Human (sf9, His) is the recombinant human-derived CD39 protein, expressed by Sf9 insect cells , with C-His labeled tag.

在神经系统中，CD39 蛋白通过水解 ATP 和其他核苷酸，充当嘌呤能神经传递的关键调节剂。其酶活性延伸至预防血小板聚集，因为它能有效地将血小板活化的 ADP 水解为 AMP。值得注意的是，CD39 在水解 ATP 和 ADP 方面表现出同等的能力，强调了其在调节嘌呤能信号通路以及促进神经传递和血小板功能的复杂调节方面的多功能作用。

Measured by its ability to hydrolyze the 5’-phosphate groups from the substrate adenosine-5’-triphosphate (ATP) and the specific activity is >5000 pmol/min/µg.

Human

Sf9 insect cells

C-His

P49961 (T38-V478)

953  [NCBI]

Approximately 56.7 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.1.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.