1. 重组蛋白
  2. CD Antigens
  3. Macrophage CD Proteins Monocyte CD Proteins Stem Cell CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins
  4. CD68
  5. CD68 蛋白, Rat (HEK293, His)

CD68 蛋白, Rat (HEK293, His)

目录号: HY-P74276
COA 产品使用指南

CD68 是属于 LAMP(溶酶体相关膜蛋白)家族的蛋白质。它主要在巨噬细胞、单核细胞和树突细胞中表达,作为这些免疫细胞的标记。CD68 蛋白, Rat (HEK293, His) 是重组的 CD68 蛋白,由 HEK293 表达,带有 C-His 标签。

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规格 价格 是否有货 数量
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5 μg ¥570 In-stock
10 μg ¥920 In-stock
50 μg ¥2380 In-stock
100 μg ¥3800 询价
> 100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

CD68 is a protein belonging to the LAMP (lysosome-associated membrane protein) family. It is expressed primarily in macrophages, monocytes, and dendritic cells, serving as a marker for these immune cells. CD68 Protein, Rat (HEK293, His) is the recombinant rat-derived CD68 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

CD68 是一种属于 LAMP(溶酶体相关膜蛋白)家族的蛋白质。它主要在巨噬细胞、单核细胞和树突细胞中表达,作为这些免疫细胞的标记。CD68 定位于溶酶体,溶酶体是负责降解各种分子的细胞器。作为一种溶酶体蛋白,CD68 在巨噬细胞和树突状细胞加工和呈递抗原中发挥着至关重要的作用。它参与吞噬作用,即这些免疫细胞吞噬和消化异物颗粒(例如细菌和细胞碎片)的过程。CD68 还与炎症和组织重塑有关,因为它的表达可以响应炎症刺激而上调。此外,CD68 已被确定为某些疾病(包括癌症)的潜在生物标志物,其表达与肿瘤进展和不良预后相关。了解 CD68 的功能和影响可以为免疫反应和疾病发病机制提供有价值的见解。

生物活性

Measured by its binding ability in a functional ELISA. When Recombinant Rat S100A8 is immobilized at 10 µg/mL (100 µL/well) can bind Recombinant Rat CD68 Protein. The ED50 for this effect is 9.492 μg/mL.

  • Measured by its binding ability in a functional ELISA. When Recombinant Rat S100A8 is immobilized at 10 µg/mL (100 µL/well) can bind Recombinant Rat CD68 Protein. The ED50 for this effect is 9.492 μg/mL.
种属

Rat

表达系统

HEK293

标签

C-6*His

蛋白编号

Q4FZY1 (K20-S295)

基因 ID
蛋白结构
N-term
CD68 (K20-S295)
Accession # Q4FZY1
His
C-term
同用名
CD68 antigenmacrophage antigen CD68; CD68; Gp110; Macrosialin; SRD1
氨基酸序列

KDCPHKKAATLLPSFTETPTTTGSTASPTTTHRPTTTSHRPTTTSHRPTTTSHRPTTTSHRPTTTSHRPTTTSHGNATVSPTTNSPGFSTVGPHPGPPPPSPSPSPSSTGALGNYTWTNGSQPCVQLQAQIQIRILYLTQGGKKAWGLSVLNPNKTKVQGGCDSAHPHLALSFPYGQLTFGFKQDRHQSHSTVYLNYMAVEYNVSFPQAAQWTFSAQNSSLQELQAPLGQSFCCGNTSIVLSPAIHLDLLSLRLQAAQLPDKGHFGPCFSCASDQS

分子量

Approximately 60-110 kDa due to the glycosylation.

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD68 Protein, Rat (HEK293, His)
目录号:
HY-P74276
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