1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Epithelial cell CD Proteins Endothelial cell CD Proteins
  4. TAPA-1/CD81
  5. CD81 蛋白, Rat (HEK293, Fc)

CD81 蛋白, Rat (HEK293, Fc)

目录号: HY-P75378
产品使用指南

CD81 是一种多功能蛋白质,参与补体调理颗粒的摄取、抑制破骨细胞形成并调节区室酶活性。在 T 细胞中,CD81 通过定位和降解 SAMHD1 来控制细胞内 dNTP 水平。此外,它还影响细胞粘附和运动,尤其是巨噬细胞。CD81 蛋白, Rat (HEK293, Fc) 是重组的 CD81 蛋白,由 HEK293 表达,带有 N-mFc 标签。

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描述

CD81, a versatile protein, participates in complement-opsonized particle ingestion, inhibits osteoclast formation, and regulates compartmentalized enzymatic activities. In T cells, CD81 controls intracellular dNTP levels by localizing and degrading SAMHD1. Moreover, it influences cell adhesion and motility, notably in macrophages. CD81 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD81 protein, expressed by HEK293 , with N-mFc labeled tag.

研究背景

CD81 是一种参与多种细胞过程的蛋白质。它在补体调理颗粒的摄入中发挥作用,防止负责骨吸收的破骨细胞的形成,并调节细胞室内的酶活性。在 T 细胞中,CD81 通过定位和降解蛋白质 SAMHD1 来帮助控制细胞内 dNTP 水平。它还涉及细胞粘附和运动,特别是巨噬细胞。

种属

Rat

表达系统

HEK293

标签

N-mFc

蛋白编号

Q62745/NP_037219.1 (K116-K201)

基因 ID
蛋白结构
N-term
mFc
CD81 (K116-K201)
Accession # Q62745/NP_037219.1
C-term
同用名
CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28
分子量

Approximately 36.2 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD81 Protein, Rat (HEK293, Fc)
目录号:
HY-P75378
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