CDCP1 蛋白, Rhesus Macaque (HEK293, His)

The CDCP1 protein has been implicated in cell adhesion and matrix association, suggesting a role in important cellular interactions. Its phosphorylation suggests a dynamic function in regulating anchorage, migration, proliferation, or differentiation. CDCP1 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CDCP1 protein, expressed by HEK293 , with C-His labeled tag.

CDCP1 蛋白似乎参与细胞粘附和细胞基质缔合，表明其在介导对细胞过程至关重要的相互作用中发挥作用。正如其磷酸化所示，它可能参与锚定与迁移或增殖与分化的调节，这意味着在调节细胞行为中发挥着动态作用。此外，CDCP1可以作为白血病诊断和未成熟造血干细胞亚群的新标记物，提供潜在的诊断和治疗见解。作为与肿瘤进展和转移有关的四跨膜蛋白网络的成员，CDCP1 与关键分子相互作用，包括 CDH2/N-钙粘蛋白、CDH3/P-钙粘蛋白、SDC1/syndecan-1、SDC4/syndecan-4、丝氨酸蛋白酶 ST14/MT -SP1、SRC 和 PRKCG/蛋白激酶 C γ。其相互作用的多样性强调了其对细胞过程的潜在影响，并表明其在正常和病理条件下具有多方面的作用。进一步探索CDCP1的功能和调节机制可以更深入地了解其对细胞动力学的贡献及其作为治疗靶点的潜力。

Immobilized Rhesus CDCP1 at 2 μg/mL(100 μl/Well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC₅₀ of ≤17.5 ng/mL determined by ELISA.

Rhesus Macaque

HEK293

C-His

XP_001114659.2 (A29-T667)

714333  [NCBI]

80-115 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.