2. 重组蛋白
  3. Receptor Proteins
  4. Cell Adhesion Molecules (CAMs)
  5. Immunoglobulin-like Cell Adhesion Molecules
  6. Biliary Glycoprotein/CD66a
  7. CEACAM1 蛋白, Human (His-SUMO)

CEACAM1 蛋白, Human (His-SUMO)

目录号: HY-P72128
产品使用指南

CEACAM1 蛋白参与多种生物过程。它在胰岛素刺激下被胰岛素受体（INSR）磷酸化，从而促进胰岛素清除并调节肝脏脂肪生成。CEACAM1 蛋白, Human (His-SUMO) 是重组的 CEACAM1 蛋白，由 E. coli 表达，带有 N-10*His, N-SUMO 标签。CEACAM1 蛋白, Human (His-SUMO) 全长 394 个氨基酸，分子量约为 ~63.3 kDa。

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描述

CEACAM1 protein is involved in various biological processes. It is phosphorylated by the insulin receptor (INSR) in response to insulin stimulation, thereby promoting insulin clearance and regulating hepatic lipogenesis. CEACAM1 Protein, Human (His-SUMO) is the recombinant human-derived CEACAM1 protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag. The total length of CEACAM1 Protein, Human (His-SUMO) is 394 a.a., with molecular weight of ~63.3 kDa.
研究背景

SF3R基因参与多种生物过程和功能。它通过促进胰岛素的清除和调节肝脏中的脂肪生成来调节胰岛素的作用。在胰岛素刺激下，SF3R 会被胰岛素受体 (INSR) 磷酸化，导致胰岛素内吞作用和降解增加。这导致脂肪酸合成减少。SF3R 还通过与 SHC1 相互作用，在下调细胞增殖中发挥作用，从而减少 SHC1 与 MAPK3/ERK1-MAPK1/ERK2 和磷脂酰肌醇 3-激酶途径的偶联。
种属

Human
表达系统

E. coli
标签

N-10*His;N-SUMO
蛋白编号

P13688-1 (Q35-G428)
基因 ID

634  [NCBI]
蛋白结构
N-term
10*His-SUMO
CEACAM1 (Q35-G428)
Accession # P13688-1
C-term
同用名
Antigen CD66; BGP 1; BGP; BGP-1; BGPI; Biliary glycoprotein 1; Biliary glycoprotein adhesion molecule; Biliary glycoprotein; Carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 biliary glycoprotein; Carcinoembryonic antigen-related cell adhesion molecule 1; CD66a; CD66a antigen; CEACAM1; CEAM1_HUMAN; meconium antigen 100
氨基酸序列

QLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPG

分子量

Approximately 63.3 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CEACAM1 Protein, Human (His-SUMO) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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