1. 重组蛋白
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Immunoglobulin-like Cell Adhesion Molecules
  5. CEA Cell Adhesion Molecule 21
  6. CEACAM21 蛋白, Human (HEK293, His)

CEACAM21 蛋白, Human (HEK293, His)

目录号: HY-P7823
产品使用指南

CEA21/CEACAM21,是一种癌胚抗原 (CEA) 相关细胞粘附分子,可在粒细胞上表达。CEACAM21 也是精神分裂症和I 型糖尿病的生物学候选基因,存在始终与疾病相关的 SNP。CEACAM21 蛋白, Human (HEK293, His) 是重组的 CEACAM21 蛋白,由 HEK293 表达,带有 C-6*His 标签。

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描述

CEA21/CEACAM21, a carcinoembryonic antigen (CEA)-related cell adhesion molecule, is expressed on granulocytes. CEACAM21 is also a biological candidate gene for schizophrenia and type I diabetes, with SNPs consistently associated with the disease. CEACAM21 Protein, Human (HEK293, His) is the recombinant human-derived CEACAM21 protein, expressed by HEK293 , with C-6*His labeled tag.

研究背景

CEA21/CEACAM21,是一种癌胚抗原 (CEA) 相关细胞粘附分子,由 CEACAM21 表达。CEA21 可能是膜的组成部分,在骨髓和淋巴结等组织中广泛表达。CEA21 是一种先天免疫受体,在粒细胞上表达并针对人类特定病原体。CEACAM21 也是精神分裂症的生物学上合理的候选基因。CEACAM21 含有一个预测内含子(该区域含有大量人类剪接的 EST 和 mRNA),存在始终与精神分裂症风险增加相关的 SNP。CEACAM21 还是 I 型糖尿病遗传学联盟候选基因,具有显著关联性。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q3KPI0-1/AAI06728.1 (W35-G240)

基因 ID
蛋白结构
N-term
CEACAM21 (W35-G240)
Accession # Q3KPI0-1/AAI06728.1
6*His
C-term
同用名
rHuCarcinoembryonic antigen-related cell adhesion molecule 21/CEACAM21, His; Carcinoembryonic antigen-related cell adhesion molecule 21; CEACAM21
氨基酸序列

WLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYTLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVVLTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHMLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKSDDNTLG

分子量

Approximately 35.0 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CEACAM21 Protein, Human (HEK293, His)
目录号:
HY-P7823
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