2. 重组蛋白
  3. CD Antigens Receptor Proteins Biotinylated Proteins
  4. Stem Cell CD Proteins Epithelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  5. CD66e/CEACAM5 Immunoglobulin-like Cell Adhesion Molecules
  6. CD66e/CEACAM5
  7. CEACAM5 蛋白, Human (Biotinylated, HEK293, C-His)

CEACAM5 蛋白, Human (Biotinylated, HEK293, C-His)

目录号: HY-P75355
产品使用指南

CEACAM5蛋白是一种细胞表面糖蛋白，与癌胚抗原相关分子（如CEACAM6）配合参与细胞粘附、细胞内信号传导和肿瘤进展。CEACAM5 蛋白, Human (Biotinylated, HEK293, C-His) 是重组的 CEACAM5 蛋白，由 HEK293 表达，带有 N-His, N-GST 标签。CEACAM5 蛋白, Human (Biotinylated, HEK293, C-His) 全长 651 个氨基酸，分子量为 100-110 kDa。

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SPR 检测服务   重组蛋白定制服务

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

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3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

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描述

CEACAM5 protein is a cell surface glycoprotein that cooperates with carcinoembryonic antigen-related molecules (such as CEACAM6) to participate in cell adhesion, intracellular signaling, and tumor progression. CEACAM5 Protein, Human (Biotinylated, HEK293, C-His) is the recombinant human-derived CEACAM5 protein, expressed by HEK293 , with N-His, N-GST labeled tag. The total length of CEACAM5 Protein, Human (Biotinylated, HEK293, C-His) is 651 a.a., with molecular weight of 100-110 kDa.
研究背景

CEACAM5 蛋白是一种细胞表面糖蛋白，在细胞粘附、细胞内信号传导和肿瘤进展中发挥多方面的作用。CEACAM5 作为嗜同性和异嗜性细胞粘附的介质，与其他癌胚抗原相关细胞粘附分子（例如 CEACAM6）相互作用。在肿瘤进展的背景下，CEACAM5 作为癌基因，促进肿瘤进展并诱导结直肠癌细胞对失巢凋亡的抵抗力。此外，在微生物感染期间，CEACAM5 充当大肠杆菌 Dr 粘附素的受体，这些粘附素的结合导致 CEACAM5 同二聚体解离。这些不同的功能强调了 CEACAM5 在调节细胞过程中的多功能性，并强调了其在生理和病理环境中的重要性。
种属

Human
表达系统

HEK293
标签

C-His
蛋白编号

NP_004354.2 (K35-A685)
基因 ID
蛋白结构
N-term
CEACAM5 (K35-A685)
Accession # NP_004354.2
His
C-term
同用名
Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e
分子量

100-110 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CEACAM5 Protein, Human (Biotinylated, HEK293, C-His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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