1. 重组蛋白
  2. Complement System
  3. Complement Regulatory Proteins
  4. Complement Factor H Related 4
  5. CFHR4 蛋白, Human (HEK293, His)

CFHR4 蛋白, Human (HEK293, His)

目录号: HY-P72690
COA 产品使用指南

CFHR4 是补体的关键调节因子,复杂地协调着补体系统。它与脂蛋白相关,表明参与脂质代谢。CFHR4 作为同二聚体,在平衡补体激活和调节方面发挥着至关重要的作用。CFHR4 蛋白, Human (HEK293, His) 是重组的 CFHR4 蛋白,由 HEK293 表达,带有 C-6*His 标签。

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规格 价格 是否有货 数量
10 μg ¥1100 In-stock
50 μg ¥3100 询价
100 μg   询价  

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描述

CFHR4, a key regulator of complement, intricately orchestrates the complement system. It associates with lipoproteins, suggesting involvement in lipid metabolism. Operating as a homodimer, CFHR4 plays a crucial role in balancing complement activation and regulation. CFHR4 Protein, Human (HEK293, His) is the recombinant human-derived CFHR4 protein, expressed by HEK293 , with C-6*His labeled tag.

研究背景

CFHR4 是补体调节的关键参与者,有助于补体系统的复杂协调。它表现出与脂蛋白结合的能力,暗示可能参与脂质代谢。作为其功能库的一部分,CFHR4 作为同二聚体发挥作用,强调其在维持补体激活和调节的微妙平衡中的作用。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q92496-1 (E20-E578)

基因 ID
蛋白结构
N-term
CFHR4 (E20-E578)
Accession # Q92496-1
6*His
C-term
同用名
Complement factor H-related protein 4; FHR-4; CFHR4; CFHL4
氨基酸序列

EVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDVEIENGFISESSSIYILNEETQYNCKPGYATAEGNSSGSITCLQNGWSTQPICIKFCDMPVFENSRAKSNGMWFKLHDTLDYECYDGYESSYGNTTDSIVCGEDGWSHLPTCYNSSENCGPPPPISNGDTTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCSNGDWSEPPRCISMKPCEFPEIQHGHLYYENTRRPYFPVATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRCE

分子量

90-110 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

CFHR4 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CFHR4 Protein, Human (HEK293, His)
目录号:
HY-P72690
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