CHIT1/Chitotriosidase-1 蛋白, Human (HEK293, His)

CHIT1/Chitotriosidase-1 protein, an enzyme degrading chitin, chitotriose, and chitobiose, potentially defends against nematodes and pathogens. Isoform 3 lacks enzymatic activity, highlighting the complexity of CHIT1 variants. The ability of CHIT1 to break down chitin suggests involvement in immune defense mechanisms. The existence of enzymatically inactive isoform 3 hints at diverse functions or regulatory roles within biological processes. CHIT1/Chitotriosidase-1 Protein, Human (HEK293, His) is the recombinant human-derived CHIT1/Chitotriosidase-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CHIT1/Chitotriosidase-1 Protein, Human (HEK293, His) is 445 a.a., with molecular weight of ~48 KDa.

CHIT1/Chitotriosidase-1 蛋白是一种能够降解几丁质、壳三糖和壳二糖的酶，表明其在防御线虫和其他病原体方面具有潜在作用。然而，值得注意的是 CHIT1 的亚型 3 缺乏酶活性。CHIT1 分解含几丁质物质的能力表明它参与免疫防御机制，特别是针对某些类型的病原体。缺乏酶活性的亚型 3 的存在强调了 CHIT1 蛋白变体的复杂性，并暗示了生物过程中潜在的不同功能或调节作用。

Measured by its ability to cleave 4-Methylumbelliferyl-beta-D-N,N’,N”-triacetylchitotriose (4-MU-TACT) that incubate at room temperature for 5 minutes. The specific activity is 2707 pmol/min/µg.

Human

HEK293

C-His

Q13231 (A22-N466)

1118  [NCBI]

Approximately 48 kDa.

Greater than 90% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of 12.5 mM Tris, 75 mM NaCl, 50% glycerol, pH 7.5.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.