1. 重组蛋白
  2. Receptor Proteins
  3. Pattern Recognition Receptors
  4. C-type Lectin Receptors
  5. BDCA-2
  6. CLEC4C 蛋白, Cynomolgus (HEK293, hFc)

CLEC4C 蛋白, Cynomolgus (HEK293, hFc)

目录号: HY-P700881
产品使用指南

CLEC4C 是一种凝集素型细胞表面受体,在树突状细胞捕获抗原中发挥着至关重要的作用。它特异性识别具有三糖表位 Gal(beta1-3/4)GlcNAc(beta1-2)Man 的非唾液酸化半乳糖封端的双触角聚糖。CLEC4C 蛋白, Cynomolgus (HEK293, hFc) 是重组的 CLEC4C 蛋白,由 HEK293 表达,带有 N-hFc 标签。CLEC4C 蛋白, Cynomolgus (HEK293, hFc) 全长 165 个氨基酸,分子量为 53-63 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

CLEC4C is a lectin-type cell surface receptor that plays a crucial role in antigen capture by dendritic cells. It specifically recognizes non-sialylated galactose-terminated biantennary glycans with the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. CLEC4C Protein, Cynomolgus (HEK293, hFc) is the recombinant cynomolgus-derived CLEC4C protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CLEC4C Protein, Cynomolgus (HEK293, hFc) is 165 a.a., with molecular weight of 53-63 kDa.

研究背景

CLEC4C 蛋白作为凝集素型细胞表面受体发挥作用,参与树突状细胞的抗原捕获。它特异性识别含有三糖表位 Gal(beta1-3/4)GlcNAc(beta1-2)Man 的非唾液酸化半乳糖封端的双触角聚糖。此外,CLEC4C 与血清 IgG 结合,并有效地将配体靶向抗原加工和肽装载区室,以呈递给 T 细胞。值得注意的是,它可能介导对浆细胞样树突状细胞中 IFN-α/β 表达诱导的有效抑制,并充当信号传导受体,激活蛋白酪氨酸激酶并动员细胞内钙。该蛋白质形成同二聚体,强调了其在细胞信号传导和免疫反应调节中的潜在重要性。

种属

Cynomolgus

表达系统

HEK293

标签

N-hFc

蛋白编号

A0A2K5UWP4 (Y48-I212)

基因 ID
蛋白结构
N-term
hFc
CLEC4C (Y48-I212)
Accession # A0A2K5UWP4
C-term
同用名
BDCA-2; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; CLEC4C; CD303; CD303; DLEC;
分子量

53-63 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CLEC4C Protein, Cynomolgus (HEK293, hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
CLEC4C Protein, Cynomolgus (HEK293, hFc)
目录号:
HY-P700881
需求量: