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  4. Coagulation Factor XI/F11 蛋白, Cynomolgus (HEK293, His)

Coagulation Factor XI/F11 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700978
产品使用指南

凝血因子XI(F11)在血液凝固的内在途径的中间阶段占据中心位置,在此阶段它承担激活因子IX的关键作用。这个复杂的过程在导致血栓形成的一系列事件中起着关键作用。Coagulation Factor XI/F11 蛋白, Cynomolgus (HEK293, His) 是重组的 凝血因子 XI/F11 蛋白,由 HEK293 表达,带有 C-His 标签。Coagulation Factor XI/F11 蛋白, Cynomolgus (HEK293, His) 全长 607 个氨基酸,分子量为 70-85 kDa。

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描述

Coagulation factor XI (F11) occupies a central position in the middle phase of the intrinsic pathway of blood coagulation, where it assumes the key role of activating factor IX. This complex process plays a key role in the chain of events that lead to the formation of a blood clot. Coagulation Factor XI/F11 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Coagulation Factor XI/F11 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor XI/F11 Protein, Cynomolgus (HEK293, His) is 607 a.a., with molecular weight of 70-85 kDa.

研究背景

凝血因子 XI,也称为 F11,在血液凝固的内在途径的中期发挥着关键作用。其关键功能在于激活因子 IX,促进一系列事件的发生,从而形成稳定的血栓。XI 因子在内在途径中的作用强调了其在止血调节中的重要性,因为它架起了上游和下游凝血因子之间的联系。

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

XP_005556540.2 (E44-A650)

基因 ID
蛋白结构
N-term
F11 (E44-A650)
Accession # XP_005556540.2
His
C-term
同用名
FXI; PTA; F11; Coagulation factor XI
分子量

70-85 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Coagulation Factor XI/F11 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Coagulation Factor XI/F11 Protein, Cynomolgus (HEK293, His)
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HY-P700978
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