DC-SIGN/CD209 蛋白, Mouse (HEK293, His)

DC-SIGN/CD209 Protein, a probable pathogen-recognition receptor, mediates the endocytosis and lysosomal degradation of pathogens. It recognizes high mannose N-linked oligosaccharides in pathogen antigens in a calcium-dependent manner and functions as a receptor for ICAM3, potentially through binding to mannose-like carbohydrates. DC-SIGN/CD209 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-His labeled tag.

DC-SIGN/CD209 蛋白是一种可能的病原体识别受体，在病原体的内吞作用中发挥作用，导致其在溶酶体区室中降解。它能够以钙依赖性方式识别各种病原体抗原中的高甘露糖N-连接寡糖。此外，它还可以作为 ICAM3 的受体，可能是通过与甘露糖样碳水化合物结合而发挥作用。

Mouse

HEK293

N-His

Q8CJ91-1 (Q74-G325)

69165  [NCBI]

Approximately 40 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.