1. 重组蛋白
  2. Receptor Proteins
  3. Notch family
  4. Delta-like 3 (DLL3)
  5. Delta-like 蛋白 3/DLL3 蛋白, Mouse (HEK293, His)

Delta-like 蛋白 3/DLL3 蛋白, Mouse (HEK293, His)

目录号: HY-P77916
COA 产品使用指南

Delta 样蛋白 3 (DLL3) 抑制初级神经发生并引导神经元走向特定的分化途径。它还有助于近轴中胚层分割中体节边界的形成。DLL3 在发育过程中的重要性体现在它结合和激活 Notch-1 或其他 Notch 受体的能力。Delta-like 蛋白 3/DLL3 蛋白, Mouse (HEK293, His) 是重组的 Delta 样蛋白 3/DLL3 蛋白,由 HEK293 表达,带有 C-His 标签。

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规格 价格 是否有货 数量
20 μg ¥2150 In-stock
50 μg ¥4200 In-stock
100 μg ¥6500 In-stock
> 100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Delta-like protein 3 (DLL3) inhibits primary neurogenesis and directs neurons towards specific differentiation pathways. It also contributes to the formation of somite boundaries in the paraxial mesoderm segmentation. DLL3's importance in developmental processes is highlighted by its ability to bind and activate Notch-1 or other Notch receptors. Delta-like protein 3/DLL3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Delta-like protein 3/DLL3 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

Delta 样蛋白 3 (DLL3) 作为初级神经发生的抑制剂发挥作用,并且可能在沿着特定分化途径转移神经元方面发挥关键作用。此外,DLL3 参与轴旁中胚层分割过程中体节边界的形成。它结合并激活 Notch-1 或其他 Notch 受体的能力强调了它在调节发育过程中的重要性。

生物活性

Immobilized Mouse DLL3, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 7.7 ng/ml determined by ELISA.

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

O88516-1 (A25-R488)

基因 ID
蛋白结构
N-term
Dll3 (A25-R488)
Accession # O88516-1
His
C-term
同用名
Delta3; DLL3; Pudgy; SCDO1; SCDO1delta3
分子量

52-60 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Delta-like protein 3/DLL3 Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Delta-like protein 3/DLL3 Protein, Mouse (HEK293, His)
目录号:
HY-P77916
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