1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. DPEP2 蛋白, Human (HEK293, Fc)

DPEP2 蛋白, Human (HEK293, Fc)

目录号: HY-P76305
产品使用指南

DPEP2 蛋白作为二肽酶发挥作用,能够将白三烯 D4 (LTD4) 水解为白三烯 E4 (LTE4) 和半胱氨酰二甘氨酸。除了其二肽酶活性外,DPEP2 还通过充当 NF-kappaB 炎症信号通路的调节剂来调节巨噬细胞炎症反应。DPEP2 蛋白, Human (HEK293, Fc) 是重组的 DPEP2 蛋白,由 HEK293 表达,带有 C-hFc 标签。

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The DPEP2 protein functions as a dipeptidase capable of hydrolyzing leukotriene D4 (LTD4) into leukotriene E4 (LTE4) and cysteinyl diglycine. In addition to its dipeptidase activity, DPEP2 serves as a modulator of macrophage inflammatory responses by acting as a modulator of the NF-kappaB inflammatory signaling pathway. DPEP2 Protein, Human (HEK293, Fc) is the recombinant human-derived DPEP2 protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

DPEP2(二肽酶 2)是一种具有二肽酶活性的多功能蛋白质,具有将白三烯 D4 (LTD4) 水解为白三烯 E4 (LTE4) 以及裂解胱氨酰双甘氨酸的能力。除了其酶功能外,DPEP2 通过充当 NF-kappaB 炎症信号通路的调节剂,在调节巨噬细胞炎症反应中发挥独立作用。这种双重功能表明 DPEP2 在细胞过程中发挥多方面的作用,既参与生物活性脂质的代谢,又参与关键炎症途径的调节,显示了其在免疫和炎症反应中的重要性。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q9H4A9-1 (A33-S376)

基因 ID
蛋白结构
N-term
DPEP2 (A33-S376)
Accession # Q9H4A9-1
hFc
C-term
同用名
Dipeptidase 2; DPEP2; Membrane-bound dipeptidase 2; MBD-2
分子量

Approximately 71.9 kDa.

纯度

Greater than 90% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

DPEP2 Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
DPEP2 Protein, Human (HEK293, Fc)
目录号:
HY-P76305
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