2. Gene
  3. DPEP2 - dipeptidase 2 Gene

DPEP2 - dipeptidase 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：二肽酶 2

种属: Homo sapiens

同用名: MBD2

基因 ID: 64174 | 基因类型: protein coding

关于 DPEP2

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,987,390-68,000,619 (from NCBI)

This gene has 9 transcripts (splice variants), 199 orthologues and 2 paralogues. Broad expression in spleen (RPKM 6.2), lymph node (RPKM 3.2) and 14 other tissues.

功能概要

DPEP2 属于膜结合二肽酶 (EC 3.4.13.19) 家族。这些酶水解多种二肽，包括白三烯 D4、某些抗生素的 β-内酰胺环，以及谷胱甘肽降解过程中形成的胱氨酰双甘氨酸 (cys-bis-gly) (Habib 等人，2003 [PubMed 12738806]) .[OMIM 提供，2008 年 3 月]

DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some Antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008]

DPEP2 基因产物(3)

mRNA Protein Name
NM_001324159.2 NP_001311088.1 dipeptidase 2 isoform 2
NM_001369657.1 NP_001356586.1 dipeptidase 2 isoform 1 precursor
NM_022355.4 NP_071750.1 dipeptidase 2 isoform 1 precursor

DPEP2 蛋白结构

Peptidase_M19

Peptidase_M19: Membrane dipeptidase (Peptidase family M19) (79 - 399)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 486 a.a.
蛋白主名 其他名称

dipeptidase 2

重组 DPEP2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76305 DPEP2 Protein, Human (HEK293, Fc) Q9H4A9-1 (A33-S376) ≥95%
HY-P76306 DPEP2 Protein, Human (HEK293, His) Q9H4A9-1 (A33-S376) ≥95%

关联疾病

疾病名称 别名
Leukoencephalopathy, Cystic, Without Megalencephaly

Cystic Leukoencephalopathy Without Megalencephaly

Rnaset2-Deficient Cystic Leukoencephalopathy

Rnase T2-Deficient Leukoencephalopathy

Clwm

Leukoencephalopathy With Bilateral Anterior Temporal Lobe Cysts

Infantile-Onset Rnaset2 Deficient Cystic Leukoencephalopathy

Lbatc

LCWM
Prolidase Deficiency

Hyperimidodipeptiduria

Imidodipeptidase Deficiency

Peptidase Deficiency

PD

Deficiency Of Prolidase

Imidodipeptiduria

Proline Dipeptidase Deficiency
Hermansky-Pudlak Syndrome 7

HPS7

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial

Delta Storage Pool Disease

Hermansky-Pudlak Syndrome, Type 7

Platelet Storage Pool Deficiency

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03948 DPEP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus DPEP2 RGD RGD:1305746
Bos taurus DPEP2 VGNC VGNC:52193
Macaca mulatta DPEP2 VGNC VGNC:71882
Mus musculus DPEP2 MGD MGI:2442042
Others DPEP2 NCBI
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