DSG2/Desmoglein-2 蛋白, Human (HEK293, His)

DSG2 is an important component of intercellular desmosome junctions and actively participates in complex interactions between plaque proteins and intermediate filaments, thereby promoting strong intercellular adhesion. By binding to these structural components, DSG-2 helps maintain cell cohesion and tissue integrity. DSG2/Desmoglein-2 Protein, Human (HEK293, His) is the recombinant human-derived DSG2/Desmoglein-2 protein, expressed by HEK293 , with C-His labeled tag.

Desmoglein-2 (DSG-2) 是细胞间桥粒连接的重要组成部分，在介导细胞间粘附方面发挥着关键作用。在这些连接处，DSG-2 参与促进斑块蛋白和中间丝之间的相互作用，有助于组织的结构完整性和稳定性。值得注意的是，DSG-2 与 Plakophilin-2 (PKP2) 形成相互作用，突显其参与负责桥粒组装和维护的复杂分子网络。这种相互作用强调了 DSG-2 在确保适当的细胞粘附和组织凝聚方面的重要性，强调其在调节各种组织细胞间连接中的关键作用。（参考：提供的资料）

Immobilized Human DSG-2 at 0.5 μg/mL (100μL/Well) on the plate. Dose response curve for Anti-DSG-2 Antibody with the EC₅₀ <19.5 ng/ml determined by ELISA.

Human

HEK293

C-His

Q14126 (A50-G609)

1829  [NCBI]

70-80 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.