1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Endothelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  4. E-Selectin/CD62E Selectin
  5. E-Selectin/CD62E
  6. E-Selectin/CD62E 蛋白, Mouse (HEK293, Fc)

E-Selectin/CD62E 蛋白, Mouse (HEK293, Fc)

目录号: HY-P73041
产品使用指南

E-选择素/CD62E 蛋白是一种细胞表面糖蛋白,通过与 SELPLG/PSGL1 相互作用介导血液中性粒细胞与细胞因子激活的内皮细胞的粘附。它还可能有助于毛细血管形态发生并与 SELPLG/PSGL1 和 PODXL2 相互作用。这些多方面的相互作用凸显了 E-选择素在细胞粘附中的作用及其对血管发育的潜在影响。E-Selectin/CD62E 蛋白, Mouse (HEK293, Fc) 是重组的 E-选择素/CD62E 蛋白,由 HEK293 表达,带有 C-hFc 标签。

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描述

E-Selectin/CD62E protein, a cell-surface glycoprotein, mediates the adhesion of blood neutrophils to cytokine-activated endothelium through interaction with SELPLG/PSGL1. It also potentially contributes to capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2. These multifaceted interactions highlight E-Selectin's role in cell adhesion and its potential influence on vascular development. E-Selectin/CD62E Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

E-选择素/CD62E 蛋白是一种细胞表面糖蛋白,通过与 SELPLG/PSGL1 相互作用介导血液中性粒细胞与细胞因子激活的内皮细胞的粘附,从而在免疫粘附中发挥至关重要的作用。除了参与免疫反应外,E-选择素还可能有助于毛细血管形态发生。该蛋白质通过唾液酸路易斯 X 表位与 SELPLG/PSGL1 和 PODXL2 相互作用,而这种相互作用似乎不需要 SELPLG 硫酸化。这些相互作用凸显了 E-选择素在介导细胞粘附事件和潜在影响与血管发育相关的过程中的多方面作用。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

NP_035475.1 (W22-P557)

基因 ID
蛋白结构
N-term
E-Selectin/CD62E (W22-P557)
Accession # NP_035475.1
hFc
C-term
同用名
E-selectin; ELAM-1; LECAM2; CD62E; SELE
分子量

Approximately 101 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
E-Selectin/CD62E Protein, Mouse (HEK293, Fc)
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HY-P73041
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