1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Endothelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  4. E-Selectin/CD62E Selectin
  5. E-Selectin/CD62E
  6. E-Selectin/CD62E 蛋白, Human (HEK293, Fc)

E-Selectin/CD62E 蛋白, Human (HEK293, Fc)

目录号: HY-P74162
产品使用指南

E-选择素/CD62E 蛋白是一种细胞表面糖蛋白,通过与 SELPLG/PSGL1 相互作用来介导中性粒细胞与细胞因子激活的内皮细胞粘附的免疫粘附。它还可能影响毛细血管形态发生,并通过唾液酸路易斯 X 表位与 SELPLG/PSGL1 和 PODXL2 相互作用,而与 SELPLG 硫酸化无关。E-Selectin/CD62E 蛋白, Human (HEK293, Fc) 是重组的 E-选择素/CD62E 蛋白,由 HEK293 表达,带有 C-hFc 标签。E-Selectin/CD62E 蛋白, Human (HEK293, Fc) 全长 535 个氨基酸,分子量约为 ~85.4 kDa。

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     可免费申领三个不同产品的试用装。

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描述

E-selectin/CD62E Protein, a cell-surface glycoprotein, crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium. It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, independently of SELPLG sulfation. E-Selectin/CD62E Protein, Human (HEK293, Fc) is the recombinant human-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-hFc labeled tag. The total length of E-Selectin/CD62E Protein, Human (HEK293, Fc) is 535 a.a., with molecular weight of ~85.4 kDa.

研究背景

E-选择素/CD62E 蛋白是一种细胞表面糖蛋白,在免疫粘附中发挥着至关重要的作用。它通过与 SELPLG/PSGL1 相互作用介导血液中性粒细胞在细胞因子激活的内皮细胞中的粘附。此外,E-选择素/CD62E 蛋白可能参与毛细血管形态发生。它通过唾液酸路易斯 X 表位与 SELPLG/PSGL1 和 PODXL2 相互作用,值得注意的是,SELPLG 硫酸化对于这种相互作用不是必需的。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

P16581 (W22-P556)

基因 ID
蛋白结构
N-term
CD62E (W22-P556)
Accession # P16581
hFc
C-term
同用名
E-selectin; ELAM-1; LECAM2; CD62E; SELE
分子量

Approximately 85.4 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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E-Selectin/CD62E Protein, Human (HEK293, Fc)
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HY-P74162
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