1. 重组蛋白
  2. Receptor Proteins
  3. ECSCR 蛋白, Human (HEK293, Fc)

ECSCR 蛋白, Human (HEK293, Fc)

目录号: HY-P77919
产品使用指南

ECSCR 蛋白在调节内皮趋化性和管形成中发挥着至关重要的作用,强调了其在血管生成中的重要性。此外,它还通过调节肌动蛋白细胞骨架并促进凋亡抑制剂 BIRC3/IAP1 和 BIRC2/IAP2 的蛋白酶体降解来促进细胞凋亡。ECSCR 蛋白与 FLNA 和 20S 蛋白酶体亚基 PSMA7 相互作用,表明它参与多个细胞过程。ECSCR 蛋白, Human (HEK293, Fc) 是重组的 ECSCR 蛋白,由 HEK293 表达,带有 C-hFc 标签。ECSCR 蛋白, Human (HEK293, Fc) 全长 100 个氨基酸,分子量为 70-80 kDa。

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100 μg   询价  

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描述

ECSCR Protein plays a crucial role in regulating endothelial chemotaxis and tube formation, emphasizing its significance in angiogenesis. Additionally, it contributes to apoptosis by modulating the actin cytoskeleton and facilitating the proteasomal degradation of apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. ECSCR Protein interacts with FLNA and the 20S proteasome subunit PSMA7, indicating its involvement in multiple cellular processes. ECSCR Protein, Human (HEK293, Fc) is the recombinant human-derived ECSCR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ECSCR Protein, Human (HEK293, Fc) is 100 a.a., with molecular weight of 70-80 kDa.

研究背景

ECSCR 蛋白在调节内皮趋化性和管形成中发挥着至关重要的作用,凸显了其在血管生成中的重要性。它还通过调节肌动蛋白细胞骨架和促进凋亡抑制剂 BIRC3/IAP1 和 BIRC2/IAP2 的蛋白酶体降解来促进细胞凋亡。ECSCR 蛋白与 FLNA 和 20S 蛋白酶体亚基 PSMA7 相互作用,表明它参与多个细胞过程。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q19T08 (Q25-A124)

基因 ID
蛋白结构
N-term
ECSCR (Q25-A124)
Accession # Q19T08
hFc
C-term
同用名
ARIA; ECSCR; ECSM2
分子量

70-80 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

ECSCR Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
ECSCR Protein, Human (HEK293, Fc)
目录号:
HY-P77919
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