1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3) Phosphatase
  4. ENPP-3 蛋白, Canine (HEK293, His)

ENPP-3 蛋白, Canine (HEK293, His)

目录号: HY-P700710
产品使用指南

ENPP-3 是一种水解酶,在调节免疫反应中起着至关重要的作用。ENPP-3 在肿瘤的发展和侵袭中起重要作用。ENPP-3 启动子区域的低甲基化通过 AKT/mTOR/4EBP1 信号通路参与卵巢子宫内膜异位症的发生和发展。ENPP-3 蛋白, Canine (HEK293, His) 是重组的 ENPP-3 蛋白,由 HEK293 表达,带有 N-His 标签。ENPP-3 蛋白, Canine (HEK293, His) 全长 829 个氨基酸,分子量为 110-130 kDa。

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描述

ENPP-3 is a hydrolase that plays a crucial role in regulating the immune response. ENPP-3 plays an important role in tumor development and invasion. The hypomethylation of the ENPP-3 promoter region is involved in the occurrence and progression of ovarian endometriosis through the AKT/mTOR/4EBP1 signaling pathway. ENPP-3 Protein, Canine (HEK293, His) is the recombinant canine-derived ENPP-3 protein, expressed by HEK293 , with N-His labeled tag. The total length of ENPP-3 Protein, Canine (HEK293, His) is 829 a.a., with molecular weight of 110-130 kDa.

研究背景

ENPP-3 是一种水解酶,具有代谢多种细胞外核苷酸的能力,包括 ATP、GTP、UTP 和 CTP。这种酶活性在调节免疫反应中起着至关重要的作用,特别是在炎症和过敏反应的慢性阶段。ENPP-3 是一种在人子宫中检测到的蛋白,在肿瘤的发展和侵袭中起重要作用。ENPP-3 启动子区域的低甲基化通过 AKT/mTOR/4EBP1 信号通路参与卵巢子宫内膜异位症的发生和发展。

种属

Canine

表达系统

HEK293

标签

N-His

蛋白编号

A0A8I3N0F5 (R46-I874)

基因 ID

/

蛋白结构
N-term
His
ENPP-3 (R46-I874)
Accession # A0A8I3N0F5
C-term
同用名
E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6; PD-Iβ
分子量

110-130 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

ENPP-3 Protein, Canine (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
ENPP-3 Protein, Canine (HEK293, His)
目录号:
HY-P700710
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