2. 重组蛋白
  3. Cytokines and Growth Factors
  4. Ephrin/Eph Family
  5. Ephrins
  6. Ephrin-A4
  7. Ephrin-A4/EFNA4 蛋白, Mouse (HEK293, Fc)

Ephrin-A4/EFNA4 蛋白, Mouse (HEK293, Fc)

目录号: HY-P70193
产品使用指南

Ephrin-A4/EFNA4 蛋白是 Eph 受体的细胞表面 GPI 结合配体，在神经元、血管和上皮发育过程中对迁移、排斥和粘附至关重要的各种细胞过程中充当关键介质。作为一种混杂结合剂，Ephrin-A4 与邻近细胞上的 Eph 受体结合，刺激向邻近细胞发出接触依赖性双向信号。Ephrin-A4/EFNA4 蛋白, Mouse (HEK293, Fc) 是重组的 Ephrin-A4/EFNA4 蛋白，由 HEK293 表达，带有 C-hFc 标签。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Ephrin-A4/EFNA4 proteins are cell surface GPI-binding ligands of Eph receptors that serve as critical mediators in a variety of cellular processes critical for migration, repulsion, and adhesion during neuronal, vascular, and epithelial development. As a promiscuous binder, Ephrin-A4 binds to Eph receptors on neighboring cells, stimulating contact-dependent bidirectional signaling to neighboring cells. Ephrin-A4/EFNA4 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Ephrin-A4/EFNA4 protein, expressed by HEK293 , with C-hFc labeled tag.
研究背景

Ephrin-A4 (EFNA4) 是一种细胞表面糖基磷脂酰肌醇 (GPI) 结合配体，属于 Eph 受体家族，是一组对各种发育过程至关重要的受体酪氨酸激酶，包括神经元、血管组织中的迁移、排斥和粘附。和上皮细胞。EFNA4 与相邻细胞上的 Eph 受体混杂结合，启动接触依赖性双向信号传导至相邻细胞。这种相互作用对于在发育过程中协调复杂的细胞事件至关重要。此外，EFNA4 可能有助于活化的 B 淋巴细胞和扁桃体中树突状细胞之间的相互作用，表明它参与免疫反应。
种属

Mouse
表达系统

HEK293
标签

C-hFc
蛋白编号

O08542 (R27-G176)
基因 ID
蛋白结构
N-term
EFNA4 (R27-G176)
Accession # O08542
hFc
C-term
同用名
rMuEphrin-A4, Fc; Ephrin-A4 ; EPH-related receptor tyrosine kinase ligand 4 ; Epl4; Eplg4; Lerk4
氨基酸序列

RHPIYWNSSNPRLLRGDAVVELGFNDYLDIFCPHYESPGPPEGPETFALYMVDWSGYEACTAEGANAFQRWNCSMPFAPFSPVRFSEKIQRYTPFPLGFEFLPGETYYYISVPTPESPGRCLRLQVSVCCKESGSSHESAHPVGSPGESG

分子量

Approximately 53.0 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Ephrin-A4/EFNA4 Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Ephrin-A4/EFNA4 Protein, Mouse (HEK293, Fc)
目录号：
HY-P70193
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z