Ephrin-B1/EFNB1 蛋白, Human (HEK293, C-hFc)

Ephrin-B1/EFNB1 Protein, a type I membrane protein, acts as a ligand for Eph-related receptor tyrosine kinases, potentially influencing cell adhesion and contributing to nervous system development. With ubiquitous expression, it is notably present in fat, placenta, and various tissues, showcasing its broad impact on diverse cellular and physiological contexts. Ephrin-B1/EFNB1 Protein, Human (HEK293, C-hFc) is the recombinant human-derived Ephrin-B1/EFNB1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Ephrin-B1/EFNB1 Protein, Human (HEK293, C-hFc) is 210 a.a., with molecular weight of approximately 58.76 kDa.

Ephrin-B1/EFNB1 蛋白是一种 I 型膜蛋白，作为 Eph 相关受体酪氨酸激酶的配体。它的参与延伸到细胞粘附的潜在作用，有助于神经系统发育或维护的复杂过程。该蛋白表现出普遍存在的表达，尤其存在于脂肪 (RPKM 27.2)、胎盘 (RPKM 17.2) 和 23 种其他组织中，凸显了其在各种细胞和生理环境中的广泛影响。

Measured in a cell proliferation assay using HUVEC cells. The ED₅₀ this effect is 2.876 ng/mL, corresponding to a specific activity is 3.4771×10^5 units/mg.

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  Measured in a cell proliferation assay using HUVEC cells. The ED₅₀ this effect is 2.876 ng/mL, corresponding to a specific activity is 3.4771×10⁵ units/mg.

Human

HEK293

C-hFc

NP_004420.1 (L28-K237)

1947  [NCBI]

LAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSK

approximately 58.76 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.