1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. ERAP2 蛋白, Human (HEK293, His)

ERAP2 蛋白, Human (HEK293, His)

目录号: HY-P75756
COA 产品使用指南

ERAP2 蛋白是一种关键的氨肽酶,在肽修剪中发挥着关键作用,对于生成与 HLA I 类分子结合的肽至关重要。通过选择性水解精氨酸 (Arg) 和赖氨酸 (Lys) 等碱性残基,ERAP2 精确定制更长的前体肽,确保在 MHC I 类分子上有效呈现的最佳长度。ERAP2 蛋白, Human (HEK293, His) 是重组的 ERAP2 蛋白,由 HEK293 表达,带有 N-His, N-10*His 标签。ERAP2 蛋白, Human (HEK293, His) 全长 905 个氨基酸,分子量为 115-125 kDa。

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规格 价格 是否有货 数量
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5 μg ¥800 In-stock
10 μg ¥1360 In-stock
50 μg ¥3800 In-stock
100 μg ¥6460 In-stock
> 100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

ERAP2 protein, a key aminopeptidase, plays a pivotal role in peptide trimming, crucial for generating peptides binding to HLA class I molecules. By selectively hydrolyzing basic residues like Arginine (Arg) and Lysine (Lys), ERAP2 precisely customizes longer precursor peptides, ensuring optimal length for effective presentation on MHC class I molecules. ERAP2 Protein, Human (HEK293, His) is the recombinant human-derived ERAP2 protein, expressed by HEK293 , with N-His, N-10*His labeled tag. The total length of ERAP2 Protein, Human (HEK293, His) is 905 a.a., with molecular weight of 115-125 kDa.

研究背景

ERAP2蛋白作为关键的氨肽酶,在肽修剪的关键过程中发挥着关键作用。此步骤对于生成大多数与 HLA I 类分子结合的肽至关重要。通过选择性水解精氨酸 (Arg) 和赖氨酸 (Lys) 等碱性残基,ERAP2 有助于精确定制较长的前体肽,确保它们达到适当的长度,以便在 MHC I 类分子上有效呈递。

生物活性

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

种属

Human

表达系统

HEK293

标签

N-His;N-10*His

蛋白编号

Q6P179-1/NP_071745.1 (A56-T960)

基因 ID
蛋白结构
N-term
His
ERAP2 (A56-T960)
Accession # Q6P179-1/NP_071745.1
C-term
中文名
重组人ERAP2蛋白
同用名
Endoplasmic reticulum aminopeptidase 2; L-RAP; ERAP2; LRAP
氨基酸序列

ATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT

分子量

115-125 kDa

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

溶液

组分

Supplied as a 0.2 μm filtered solution of 12.5 mM Tris-HCL, 75 mM NaCl, pH 7.5, 50% Glycerol.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料

ERAP2 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
ERAP2 Protein, Human (HEK293, His)
目录号:
HY-P75756
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