Exfoliative toxin A 蛋白, S. aureus (His)

Exfoliative toxin A protein, with serine protease-like properties, binds to skin protein profilaggrin, demonstrating cleavage activity after acidic residues. Its involvement is associated with impetigous diseases, particularly staphylococcal scalded skin syndrome (SSSS). Exfoliative toxin A Protein, S. aureus (His) is the recombinant Staphylococcus aureus-derived Exfoliative toxin A protein, expressed by E. coli , with N-6*His labeled tag. The total length of Exfoliative toxin A Protein, S. aureus (His) is 242 a.a., with molecular weight of ~30.9 kDa.

剥脱性毒素 A 蛋白具有丝氨酸蛋白酶样特性，并且具有与皮肤蛋白聚丝蛋白原结合的亲和力。它特别在酸性残基后表现出裂解活性。值得注意的是，剥脱性毒素，包括剥脱性毒素 A，与引起通常称为葡萄球菌烫伤皮肤综合征 (SSSS) 的脓疱病有关。

Staphylococcus aureus

E. coli

N-6*His

P09331 (E39-E280)

/

EVSAEEIKKHEEKWNKYYGVNAFNLPKELFSKVDEKDRQKYPYNTIGNVFVKGQTSATGVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVKEILQEPFGAGVDLALIRLKPDQNGVSLGDKISPAKIGTSNDLKDGDKLELIGYPFDHKVNQMHRSEIELTTLSRGLRYYGFTVPGNSGSGIFNSNGELVGIHSSKVSHLDREHQINYGVGIGNYVKRIINEKNE

Approximately 30.9 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against solution in 20 mM Tris-HC1, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.