1. 重组蛋白
  2. CD Antigens Fc Receptors Biotinylated Proteins
  3. Macrophage CD Proteins Monocyte CD Proteins Platelet CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins Fc-gamma Receptor
  4. Fc gamma RII/CD32
  5. FcγRIIB/CD32b
  6. Fc gamma RIIB/CD32b 蛋白, Human (Biotinylated, HEK293, His-Avi)

Fc gamma RIIB/CD32b 蛋白, Human (Biotinylated, HEK293, His-Avi)

目录号: HY-P75211
产品使用指南

Fc gamma RIIB/CD32b 蛋白是免疫球蛋白 gamma 的低亲和力受体,在免疫反应中发挥关键作用。它介导免疫复合物的吞噬作用并调节 B 细胞的抗体产生。Fc gamma RIIB/CD32b 蛋白, Human (Biotinylated, HEK293, His-Avi) 是重组的 Fc gamma RIIB/CD32b 蛋白,由 HEK293 表达,带有 C-Avi, C-His 标签。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Fc gamma RIIB/CD32b protein is a low-affinity receptor for immunoglobulin gamma and plays a key role in immune responses. It mediates phagocytosis of immune complexes and regulates antibody production by B cells. Fc gamma RIIB/CD32b Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Fc gamma RIIB/CD32b protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

研究背景

Fc gamma RIIB/CD32b 蛋白充当复合或聚集的免疫球蛋白 gamma Fc 区的受体,显示出低亲和力。它在各种效应器和调节功能中发挥着关键作用,包括免疫复合物的吞噬作用和 B 细胞抗体产生的调节。与该受体结合后,B 细胞 (BCR)、T 细胞 (TCR) 或其他 Fc 受体上的抗原受体触发先前的细胞激活状态下调。值得注意的是,异构体 IIB1 不能介导内吞作用或吞噬作用,而异构体 IIB2 不诱导吞噬作用。Fc gamma RIIB/CD32b 与 INPP5D/SHIP1、FGR 和 LYN 相互作用。

种属

Human

表达系统

HEK293

标签

C-Avi;C-His

蛋白编号

P31994-2/NP_001002274.1 (A46-I224)

基因 ID
蛋白结构
N-term
CD32b (A46-I224)
Accession # P31994-2/NP_001002274.1
Avi-His
C-term
同用名
Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; FcRII-b; CD32; FCGR2B; FCG2; IGFR2
分子量

30-35 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Fc gamma RIIB/CD32b Protein, Human (Biotinylated, HEK293, His-Avi)
目录号:
HY-P75211
需求量: