FCRL2 蛋白, Human (HEK293, C-His)

The FCRL2 protein regulates normal and neoplastic B cell development and has been shown to be involved in complex processes that control B cell maturation. Its tyrosine-phosphorylated isoform 2 interacts with PTPN6, suggesting the existence of a signaling pathway and emphasizing the role of this protein in cellular regulation. FCRL2 Protein, Human (HEK293, C-His) is the recombinant human-derived FCRL2, expressed by HEK293 , with C-6*His labeled tag. The total length of FCRL2 Protein, Human (HEK293, C-His) is 376 a.a.,

FCRL2 蛋白似乎在正常和肿瘤性 B 细胞发育中都具有调节作用，表明它参与了控制 B 细胞成熟和功能的复杂过程。特别是，已知 FCRL2 的酪氨酸磷酸化亚型 2 与 PTPN6 相互作用，表明存在潜在的信号传导途径并强调了该蛋白质在细胞调节中的作用。FCRL2 影响 B 细胞发育的具体机制及其与 PTPN6 的相互作用仍然是人们感兴趣的领域，强调了该蛋白质在免疫系统过程中的重要性及其在 B 细胞相关疾病中的潜在相关性。

Immobilized Recombinant Human FCRL2 at 4 μg/mL (100 μL/well) can bind Human IgG. The KD for this effect is 76.8 nM.

Human

HEK293

C-6*His

Q96LA5-1 (L20-D395)

79368

LTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRD

Approximately 55-70 kDa due to the glycosylation

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.