2. 重组蛋白
  3. Cytokines and Growth Factors CD Antigens Receptor Proteins Enzymes & Regulators
  4. FGF Family Stem Cell CD Proteins Epithelial cell CD Proteins Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. FGFR-3 FGFR
  6. FGFR-3
  7. FGFR-3 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)

FGFR-3 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)

目录号: HY-P76341
产品使用指南

FGFR-3 是成纤维细胞生长因子受体家族的一员，在软骨、脑、肠和肾等组织中表达。FGFR-3 通过激活 MAPK/STAT 信号通路调控软骨细胞分化和软骨细胞增殖。FGFR-3 是一种肿瘤标志物。FGFR-3 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc) 是重组的 FGFR-3 蛋白，由 HEK293 表达，带有 C-hFc 标签。

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规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

FGFR-3 is a member of the fibroblast growth factor receptor family and is expressed in tissues such as cartilage, brain, intestine and kidney. FGFR-3 regulates chondrocyte differentiation and proliferation by activating the MAPK/STAT signaling pathway. FGFR-3 is a tumor marker. FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant cynomolgus-derived FGFR-3 protein, expressed by HEK293 , with C-hFc labeled tag.
研究背景

FGFR-3 是成纤维细胞生长因子受体家族的一员，在软骨、脑、肠和肾等组织中表达。FGFR-3 蛋白通过调节骨化在骨生长中发挥作用。FGFR-3 是软骨内和膜性骨化的重要调节因子，是长骨生长的负调节因子。FGFR-3 通过激活 MAPK/STAT 信号通路调控软骨细胞分化和软骨细胞增殖。FGFR-3 是一种肿瘤标志物。
种属

Cynomolgus
表达系统

HEK293
标签

C-hFc
蛋白编号

F7FZR9/XP_001101108.1 (E23-G375)
基因 ID
蛋白结构
N-term
FGFR-3 (E23-G375)
Accession # F7FZR9/XP_001101108.1
hFc
C-term
同用名
Fibroblast growth factor receptor 3; FGFR-3; CD333; Mfr3; Sam3
分子量

Approximately 99.9 kDa.
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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