2. Gene
  3. FGFR3 - fibroblast growth factor receptor 3 Gene

FGFR3 - fibroblast growth factor receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：成纤维细胞生长因子受体 3

种属: Macaca mulatta

基因 ID: 712829 | 基因类型: protein coding

关于 FGFR3

Primary_assembly 5: 1,850,684-1,864,251 forward strand.Mmul_10:CM014340.1

This gene has 2 transcripts (splice variants), 191 orthologues and 53 paralogues.

FGFR3 基因产物(12)

mRNA Protein Name
XM_015137851.2 XP_014993337.1 fibroblast growth factor receptor 3 isoform X11
XM_015137844.2 XP_014993330.1 fibroblast growth factor receptor 3 isoform X2
XM_028848225.1 XP_028704058.1 fibroblast growth factor receptor 3 isoform X12
XM_015137843.2 XP_014993329.1 fibroblast growth factor receptor 3 isoform X1
XM_001101108.4 XP_001101108.1 fibroblast growth factor receptor 3 isoform X10
XM_015137847.2 XP_014993333.1 fibroblast growth factor receptor 3 isoform X4
XM_015137848.2 XP_014993334.1 fibroblast growth factor receptor 3 isoform X5
XM_002802167.3 XP_002802213.1 fibroblast growth factor receptor 3 isoform X6
XM_015137850.2 XP_014993336.1 fibroblast growth factor receptor 3 isoform X8
XM_015137846.2 XP_014993332.1 fibroblast growth factor receptor 3 isoform X3
XM_028848223.1 XP_028704056.1 fibroblast growth factor receptor 3 isoform X7
XM_028848224.1 XP_028704057.1 fibroblast growth factor receptor 3 isoform X9

FGFR3 蛋白结构

Ig

Ig: cl11960 (42 - 108)

Ig

Ig: cd00096 (56 - 60)

Ig

Ig: cd00096 (68 - 74)

Ig

Ig: cd00096 (91 - 95)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (150 - 153)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (150 - 244)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (161 - 166)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (170 - 178)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (184 - 189)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (192 - 194)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (203 - 206)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (210 - 215)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (224 - 231)

IgI_2_FGFR

IgI_2_FGFR: cd05857 (234 - 244)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (252 - 353)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (252 - 255)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (259 - 263)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (271 - 278)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (282 - 289)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (304 - 309)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (320 - 325)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (333 - 341)

IgI_3_FGFR

IgI_3_FGFR: cd04974 (344 - 352)

PKc_like

PKc_like: cl21453 (462 - 795)

  • 0
  • 200
  • 400
  • 600
  • 810 a.a.
蛋白主名 其他名称

fibroblast growth factor receptor 3

重组 FGFR3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76341 FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) F7FZR9/XP_001101108.1 (E23-G375) ≥95%
HY-P76342 FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) F7FZR9/XP_001101108.1 (E23-G375) ≥95%

相关产品

Approval
生物活性分子 (9)
目录号 产品名 作用方式
纯度 是否罕见病
HY-10981 Lenvatinib Inhibitor 99.85% 是
HY-50904 Nintedanib Inhibitor 99.94% 是
HY-18708 Erdafitinib Inhibitor 99.66% 否
HY-13311 Infigratinib Inhibitor 99.82% 是
HY-109099 Pemigatinib Inhibitor 99.84% 是
HY-100818 Futibatinib Inhibitor 99.65% 否
HY-11106 Nintedanib esylate Inhibitor 99.96% 是
HY-10981A Lenvatinib mesylate Inhibitor 99.86% 是
HY-13311A Infigratinib phosphate Inhibitor 99.74% 是
Clinical Phase
生物活性分子 (16)
目录号 产品名 作用方式
纯度 Phase
HY-13330 Fexagratinib Inhibitor 99.85% Phase 3
HY-50905 Dovitinib Inhibitor 99.88% Phase 3
HY-100019 Rogaratinib Inhibitor 99.86% Phase 3
HY-10207 Dovitinib lactate Inhibitor 99.75% Phase 3
HY-B0062 Dovitinib lactate hydrate Inhibitor / Phase 3
HY-101568 Roblitinib Inhibitor 99.74% Phase 2
HY-13034 Gandotinib Inhibitor 99.86% Phase 2
HY-19981 Derazantinib Inhibitor 99.28% Phase 2
HY-19957 Zoligratinib Inhibitor 99.76% Phase 2
HY-159642 TYRA-300 Inhibitor 99.90% Phase 2
HY-101466A E7090 succinate Inhibitor 99.17% Phase 2
HY-13304 LY2874455 Inhibitor 99.14% Phase 1
HY-101768 PRN1371 Inhibitor 99.43% Phase 1
HY-119367 ODM-203 Inhibitor 99.91% Phase 1
HY-19983 ASP5878 Inhibitor 99.69% Phase 1
HY-131908 CPL304110 Inhibitor 99.85% Phase 1
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99384 Vofatamab Inhibitor 98.32% Phase 2
HY-P99823 Recifercept 97.10% Phase 2
Pre-clinical Phase
生物活性分子 (33)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12823 BLU9931 Inhibitor 99.97% 否
HY-10032 PF 477736 Inhibitor 99.21% 否
HY-18602 FIIN-2 Inhibitor 99.32% 否
HY-145231 FGFR2-IN-2 Inhibitor 98.25% 否
HY-148779 FGFR3-IN-5 Inhibitor 99.28% 否
HY-15599 SSR128129E Inhibitor 99.85% 否
HY-101466 E7090 Inhibitor 99.64% 否
HY-100491 H3B-6527 Inhibitor ≥98.0% 否
HY-15813 FIIN-1 Inhibitor 99.11% 否
HY-P3695 VSPPLTLGQLLS Inhibitor 98.81% 否
HY-18603 FIIN-3 Inhibitor 99.66% 否
HY-108933 JK-P3 Inhibitor 99.72% 否
HY-12965 S49076 Inhibitor 99.44% 否
HY-P3695A VSPPLTLGQLLS TFA Inhibitor / 否
HY-147714 FGFR3-IN-2 Inhibitor / 否
HY-170919 FGFR2/3-IN-2 Inhibitor / 否
HY-147713 FGFR3-IN-1 Inhibitor / 否
HY-152104 FGFR-IN-9 Inhibitor / 否
HY-152146 HDAC-IN-50 Inhibitor / 否
HY-151903S FGFR2/3-IN-1 Inhibitor / 否
HY-147715 FGFR3-IN-3 Inhibitor / 否
HY-142921 FGFR-IN-2 Inhibitor / 否
HY-156790 FGFR3-IN-6 Inhibitor / 否
HY-148778 FGFR3-IN-4 Inhibitor / 否
HY-170846 FGFRs-IN-1 Inhibitor / 否
HY-150652 FGFR-IN-8 Inhibitor / 否
HY-158248 FGFR4-IN-19 Inhibitor / 否
HY-155028 FGFR-IN-11 Inhibitor / 否
HY-156791 FGFR3-IN-7 Inhibitor / 否
HY-164459 AZ8010 Inhibitor / 否
HY-159642G TYRA-300 (GMP) Inhibitor / 否
HY-159503A Segigratinib hydrochloride Inhibitor / 否
HY-15599A SSR128129E free acid Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens FGFR3 NCBI NCBI:2261
Mus musculus FGFR3 NCBI NCBI:14184
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